Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.48 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | SCN7A | Q01118 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727011 | 0.95 | PDE4B (0.50) | PDE4BPARP15PARP10KDM2BSCN7A | |
| SCHEMBL3721101 | 0.93 | PDE4B (0.44) | PDE4BSRCPARP15PARP10KDM2B | |
| SCHEMBL3726878 | 0.89 | PDE4B (0.48) | PDE4BSRCPARP15PARP10SCN7A | |
| SCHEMBL3721143 | 0.87 | PDE4B (0.51) | PDE4BPARP15PARP10KDM2BSCN7A | |
| SCHEMBL3717216 | 0.84 | PDE4B (0.52) | PDE4BSCN7AKCNH2SCN9AMEN1 | |
| SCHEMBL3721926 | 0.84 | PDE4B (0.44) | PDE4BSRCPARP15PARP10KDM2B | |
| SCHEMBL3725384 | 0.84 | PDE4B (0.50) | PDE4BKDM2B | |
| SCHEMBL3720845 | 0.84 | MTNR1A (0.46) | SRCSCN9AMEN1KMT2A | |
| SCHEMBL3720844 | 0.84 | ACACA (0.48) | SRC | |
| SCHEMBL3721299 | 0.83 | PDE4B (0.51) | PDE4BSCN7AKCNH2SCN9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |