Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.43 |
| ▸ | ACACB | O00763 | 5/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719600 | 0.93 | PDE4B (0.48) | PDE4BPARP10PARP15KDM2BSRC | |
| SCHEMBL3721926 | 0.90 | PDE4B (0.44) | PDE4BPARP10PARP15ACACBSLC2A1 | |
| SCHEMBL3727011 | 0.88 | PDE4B (0.50) | PDE4BPARP10PARP15ACACBKDM2B | |
| SCHEMBL3721143 | 0.87 | PDE4B (0.51) | PDE4BPARP10PARP15ACACBKDM2B | |
| SCHEMBL3724232 | 0.85 | PDE4B (0.46) | PDE4BPARP10PARP15ACACBKDM2B | |
| SCHEMBL3721408 | 0.84 | PDE4B (0.47) | PDE4BMEN1KMT2A | |
| SCHEMBL3720427 | 0.84 | ACACB (0.56) | PDE4BPARP10PARP15ACACBKDM2B | |
| SCHEMBL3720495 | 0.84 | MTNR1A (0.46) | PARP10PARP15ACACBCYP3A4CYP2C9 | |
| SCHEMBL3720493 | 0.84 | ACACA (0.50) | ACACBCYP3A4CYP2C9ACACA | |
| SCHEMBL3726878 | 0.83 | PDE4B (0.48) | PDE4BPARP10PARP15ACACBSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |