Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.45 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3725123 | 0.80 | ADAM17 (0.61) | ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL397852 | 0.78 | CFTR (0.66) | ALDH1A1MAPTKMT2AROCK1MEN1 | |
| SCHEMBL3721485 | 0.75 | SMN1; SMN2 (0.67) | MAPTLMNAKMT2AMEN1 | |
| SCHEMBL12123854 | 0.74 | ALDH1A1 (0.60) | ALDH1A1MAPTKDM4ELMNAKMT2A | |
| SCHEMBL30964171 | 0.74 | MAPT (0.80) | ALDH1A1MAPTKDM4ELMNAKMT2A | |
| SCHEMBL6625019 | 0.72 | L3MBTL1 (0.58) | ALDH1A1MAPTKDM4EL3MBTL1RPS6KA3 | |
| SCHEMBL30964163 | 0.72 | MAPT (0.61) | ALDH1A1MAPTKDM4ELMNAKMT2A | |
| SCHEMBL22500324 | 0.72 | MAPT (0.70) | ALDH1A1MAPTKDM4ELMNAKMT2A | |
| SCHEMBL22500323 | 0.72 | MAPT (0.70) | ALDH1A1MAPTKDM4ELMNAKMT2A | |
| SCHEMBL30964188 | 0.72 | MAPT (0.70) | ALDH1A1MAPTKDM4ELMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139982-A1 | INDOLE DERIVATIVES FOR THE STIMULATION OF STEM CELL PROLIFERATION | THE UNIVERSITY OF SHEFFIELD (GB) | 2010-12-09 | — | — | WO | disclosed |
| WO-2010139982-A1 | INDOLE DERIVATIVES FOR THE STIMULATION OF STEM CELL PROLIFERATION | THE UNIVERSITY OF SHEFFIELD (GB) | 2010-12-09 | — | — | WO | disclosed |