Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | GABRP | O00591 | 1/20 | 0.59 |
| ▸ | GABRD | O14764 | 1/20 | 0.59 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.59 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.59 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.59 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.59 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.59 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.59 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.59 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.59 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.59 |
| ▸ | GABRE | P78334 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3725123 | 0.85 | ADAM17 (0.61) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL15979987 | 0.80 | CTNNB1 (0.72) | SMN1; SMN2RAB9AMAPTNPC1MEN1 | |
| SCHEMBL11924588 | 0.79 | RAB9A (0.76) | SMN1; SMN2RAB9AMAPTNPC1MEN1 | |
| SCHEMBL6363764 | 0.77 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9AMAPTNPC1MEN1 | |
| SCHEMBL8534922 | 0.76 | SMN1; SMN2 (1.00) | SMN1; SMN2RAB9AMAPTNPC1MEN1 | |
| SCHEMBL5162760 | 0.76 | NR4A2 (0.67) | SMN1; SMN2RAB9AMAPTNPC1MEN1 | |
| SCHEMBL29456920 | 0.76 | NR4A2 (0.67) | SMN1; SMN2RAB9AMAPTNPC1MEN1 | |
| SCHEMBL3722135 | 0.75 | ALDH1A1 (0.61) | MAPTMEN1KMT2ALMNA | |
| SCHEMBL7006163 | 0.75 | DRD2 (0.73) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL399071 | 0.75 | CFTR (0.74) | GABRA1GABRB1GABRA5GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139982-A1 | INDOLE DERIVATIVES FOR THE STIMULATION OF STEM CELL PROLIFERATION | THE UNIVERSITY OF SHEFFIELD (GB) | 2010-12-09 | — | — | WO | disclosed |
| WO-2010139982-A1 | INDOLE DERIVATIVES FOR THE STIMULATION OF STEM CELL PROLIFERATION | THE UNIVERSITY OF SHEFFIELD (GB) | 2010-12-09 | — | — | WO | disclosed |