Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 6/20 | 0.38 |
| ▸ | RARB | P10826 | 6/20 | 0.38 |
| ▸ | RARG | P13631 | 6/20 | 0.38 |
| ▸ | MELK | Q14680 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718741 | 0.85 | MELK (0.38) | MELKGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3633710 | 0.77 | MELK (0.39) | MELKGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9532118 | 0.71 | ALDH1A1 (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2098385 | 0.70 | RARA (0.39) | RARARARBRARG | |
| SCHEMBL381965 | 0.69 | ALDH1A1 (0.41) | RARARARBRARGHSP90AA1HSP90AB1 | |
| SCHEMBL381769 | 0.69 | RARA (0.39) | RARARARBRARGHSP90AA1HSP90AB1 | |
| SCHEMBL3722583 | 0.69 | RARA (0.40) | RARARARBRARGMELKGABRP | |
| SCHEMBL1860548 | 0.68 | RARA (0.48) | RARARARBRARGHSP90AA1HSP90AB1 | |
| SCHEMBL1746302 | 0.67 | RARB (0.52) | RARBRARGMELKGABRPGABRD | |
| SCHEMBL2098396 | 0.67 | RARB (0.50) | RARARARBRARGHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146951-A2 | NOVEL RAR RECEPTOR AGONIST LIGANDS AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS | Galderma Research & Development (FR) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008152260-A2 | NOVEL RAR RECEPTOR AGONIST LIGANDS AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2008-12-18 | — | — | WO | disclosed |