Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 3/20 | 0.40 |
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | RARG | P13631 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 4/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRE | P78334 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29149564 | 0.78 | ALDH1A1 (0.49) | HRH3LMNAALDH1A1KDM4ETDP1 | |
| SCHEMBL3718741 | 0.71 | MELK (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9533473 | 0.71 | HRH3 (0.51) | HRH3LMNAALDH1A1KDM4ETDP1 | |
| SCHEMBL2099433 | 0.69 | RBP4 (0.37) | RARARARBRARGRBP4ALDH1A1 | |
| SCHEMBL14200003 | 0.69 | CYP2C9 (0.41) | RARARARBRARGRBP4LMNA | |
| SCHEMBL19937820 | 0.69 | ALDH1A1 (0.53) | RARARARBRARGRBP4ALDH1A1 | |
| SCHEMBL15726858 | 0.69 | ALDH1A1 (0.45) | RARARARBRARGRBP4ALDH1A1 | |
| SCHEMBL382856 | 0.69 | RBP4 (0.58) | RARARARBRARGRBP4LMNA | |
| SCHEMBL382827 | 0.69 | RBP4 (0.39) | RARARARBRARGRBP4ALDH1A1 | |
| SCHEMBL3722540 | 0.69 | RARA (0.38) | RARARARBRARGGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146951-A2 | NOVEL RAR RECEPTOR AGONIST LIGANDS AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS | Galderma Research & Development (FR) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008152260-A2 | NOVEL RAR RECEPTOR AGONIST LIGANDS AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2008-12-18 | — | — | WO | disclosed |