Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | MPI | P34949 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27927704 | 0.98 | ALDH1A1 (0.60) | ALDH1A1CYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL6657329 | 0.89 | ALDH1A1 (0.55) | ALDH1A1CYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL372692 | 0.86 | ALDH1A1 (0.52) | ALDH1A1CYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL27450472 | 0.84 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL6130589 | 0.83 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL13359392 | 0.82 | ALOX5 (0.53) | ALDH1A1GAAMAPTSMN1; SMN2LMNA | |
| SCHEMBL15722176 | 0.81 | ALDH1A1 (0.51) | ALDH1A1GAAMAPTSMN1; SMN2LMNA | |
| SCHEMBL6304224 | 0.81 | CYP1A2 (0.61) | ALDH1A1CYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL30129703 | 0.81 | CYP1A2 (0.61) | ALDH1A1CYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL4488260 | 0.79 | ALDH1A1 (0.70) | ALDH1A1CYP1A2CYP2C19CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 665 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583915-B | Quinoline chalcone derivative, synthesis method and application thereof | 云南中医药大学 | 2025-01-10 | — | — | CN | claimed |
| CN-114957113-B | 2-chloroquinoline-3-formaldehyde oxime-O- (N-p-fluorophenyl) carbamate and preparation method and application thereof | 渤海大学 | 2023-05-09 | — | — | CN | claimed |
| CN-115583915-A | Quinoline chalcone derivative, and synthesis method and application thereof | 云南中医药大学 | 2023-01-10 | — | — | CN | claimed |
| CN-113214182-B | Benzisothiazole compound and preparation method thereof | 佛山湘潭大学绿色智造研究院 | 2022-12-23 | — | — | CN | claimed |
| CN-114957113-A | 2-chloroquinoline-3-formaldehyde oxime-O- (N-p-fluorophenyl) carbamate and preparation method and application thereof | 渤海大学 | 2022-08-30 | — | — | CN | claimed |
| CN-113214182-A | Benzisothiazole compound and preparation method thereof | 佛山湘潭大学绿色智造研究院 | 2021-08-06 | — | — | CN | claimed |
| CN-106831566-B | A kind of preparation method of the chloro- 3- formyl quinoline analog derivative of 2- | 三峡大学 | 2019-11-08 | — | — | CN | claimed |
| CN-106423264-B | The preparation method and its spare magnetic acidity nanometer material catalyst processed of a kind of quinoline, the derivative | 马鞍山市泰博化工科技有限公司 | 2019-09-10 | — | — | CN | claimed |
| CN-110041305-A | Half cyanines fluorescence probe of indoles, preparation method and the application in cyanide ion detection | 三峡大学 | 2019-07-23 | — | — | CN | claimed |
| CN-106967077-B | A kind of chromene simultaneously [2,3-b] quinoline and its preparation method and application | 江苏理工学院 | 2019-02-19 | — | — | CN | claimed |
| CN-105223171-B | A kind of synthesis of near-infrared phosphorescent iridium complex and its fluoroscopic examination imaging applications | 赣南师范大学 | 2018-03-27 | — | — | CN | claimed |
| CN-107098914-A | A kind of chromene simultaneously [3 ', 4 ':5,6] pyrans simultaneously [2,3 b] quinoline and its preparation method and application | 江苏理工学院 | 2017-08-29 | — | — | CN | claimed |
| CN-106967077-A | A kind of chromene simultaneously [2,3 b] quinoline and its preparation method and application | 江苏理工学院 | 2017-07-21 | — | — | CN | claimed |
| CN-106423264-A | Quinoline derivative, preparation method thereof and magnetic-acidic nano material catalyst for preparation | 马鞍山市泰博化工科技有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-106334578-A | Quinoline derivative, synthesis method of derivative and catalyst for synthesis | 马鞍山市泰博化工科技有限公司 | 2017-01-18 | — | — | CN | claimed |
| CN-105223171-A | A kind of synthesis of near infrared phosphorescent iridium complex and fluoroscopic examination imaging applications thereof | GANNAN NORMAL UNIVERSITY | 2016-01-06 | — | — | CN | claimed |
| US-20100285124-A1 | TETRAHYDROCYCLOPENTA[C]ACRIDINE DERIVATIVES AS KINASE INHIBITORS AND BIOLOGICAL | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-11-11 | — | — | US | claimed |
| CN-1958572-A | Compound in category of dihydro quinolines, preparation method, and composition of medication | SHANGHAI INST OF MEDICINE C A (CN) | 2007-05-09 | — | — | CN | claimed |
| US-12559504-B2 | Benzotriazole derivative | UBE CORPORATION (JP) | 2026-02-24 | — | — | US | disclosed |
| EP-0120483-A1 | (1H-tetrazol-5-yl)-2(1H)-quinolinones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-10-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12559504-B2 | Benzotriazole derivative | KEAP1, NFE2L2, NCOR1 | ALDH1A1 198/4885CYP1A2 350/4885CYP2C19 1419/4885 |
| US-20100285124-A1 | TETRAHYDROCYCLOPENTA[C]ACRIDINE DERIVATIVES AS KINASE INHIBITORS AND BIOLOGICAL | ALK, MAPK3, MAP3K9 | ALDH1A1 3660/4885CYP1A2 2069/4885CYP2C19 1458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.