Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.39 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30320420 | 0.82 | ERN1 (0.62) | ERN1HTTALDH1A1MAPTTDP1 | |
| SCHEMBL286441 | 0.82 | ERN1 (0.62) | ERN1HTTALDH1A1MAPTTDP1 | |
| SCHEMBL27787985 | 0.79 | ERN1 (0.53) | ERN1HTTALDH1A1MAPTTDP1 | |
| SCHEMBL8329402 | 0.79 | ERN1 (0.57) | ERN1HTTALDH1A1MAPTKDM4E | |
| SCHEMBL1669597 | 0.78 | ALDH1A1 (0.50) | ERN1HTTALDH1A1MAPTKMT2A | |
| SCHEMBL14384260 | 0.75 | ERN1 (0.49) | ERN1HTTALDH1A1MAPTTDP1 | |
| SCHEMBL14035620 | 0.75 | MAPT (0.57) | ERN1HTTALDH1A1MAPTTDP1 | |
| SCHEMBL5655380 | 0.75 | ALDH1A1 (0.47) | ERN1HTTALDH1A1MAPTTDP1 | |
| SCHEMBL8964120 | 0.74 | LMNA (0.56) | ERN1ALDH1A1MAPTTDP1KDM4E | |
| SCHEMBL28077654 | 0.74 | KMT2A (0.59) | ERN1HTTALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010092030-A1 | TIME-TEMPERATURE INDICATOR BASED ON THIOALKYL AND THIOARYL SUBSTITUTED SPIROAROMATICS | FRESHPOINT HOLDINGS SA (CH) | 2010-08-19 | — | — | WO | disclosed |