Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.60 |
| ▸ | MAOA | P21397 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | RXRA | P19793 | 1/20 | 0.52 |
| ▸ | RXRB | P28702 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15763863 | 0.89 | CREBBP (0.54) | ALDH1A1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL7737574 | 0.83 | MAOB (0.62) | MAOBMAOAALDH1A1NPC1MAPT | |
| SCHEMBL7739310 | 0.83 | NPC1 (0.63) | MAOBMAOAALDH1A1NPC1MAPT | |
| SCHEMBL1391084 | 0.79 | ALDH1A1 (0.55) | MAOBALDH1A1NPC1MAPTLMNA | |
| SCHEMBL10306524 | 0.78 | L3MBTL1 (0.61) | ALDH1A1MAPTLMNARAB9AL3MBTL1 | |
| SCHEMBL11813952 | 0.78 | KMT2A (0.57) | ALDH1A1NPC1MAPTLMNARAB9A | |
| SCHEMBL166144 | 0.78 | L3MBTL1 (0.70) | MAOBMAOAALDH1A1NPC1MAPT | |
| SCHEMBL867738 | 0.77 | KDM4E (0.66) | LMNASMN1; SMN2L3MBTL1RXRARXRB | |
| SCHEMBL3722774 | 0.77 | RAB9A (0.49) | MAOBMAOAALDH1A1NPC1MAPT | |
| SCHEMBL6963814 | 0.77 | MAOB (0.69) | MAOBMAOAALDH1A1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |