Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.59 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11746659 | 0.96 | PTGS1 (0.56) | PTGS1AKR1C3AKR1C2CYP1A2KDM4E | |
| SCHEMBL616311 | 0.84 | CYP1A2 (0.59) | PTGS1AKR1C3AKR1C2CYP1A2KDM4E | |
| SCHEMBL616083 | 0.83 | ALDH1A1 (0.69) | PTGS1AKR1C3AKR1C2CYP1A2KDM4E | |
| SCHEMBL11741327 | 0.82 | PTGS1 (0.49) | PTGS1AKR1C3AKR1C2CYP1A2KDM4E | |
| SCHEMBL30594477 | 0.81 | AKR1C3 (0.46) | PTGS1AKR1C3AKR1C2CYP1A2KDM4E | |
| SCHEMBL190915 | 0.81 | ALDH1A1 (0.65) | TP53CYP3A4SMN1; SMN2CYP2A6ALDH1A1 | |
| SCHEMBL27513322 | 0.80 | PTGS1 (0.54) | PTGS1AKR1C3AKR1C2CYP1A2KDM4E | |
| SCHEMBL11741420 | 0.80 | ALDH1A1 (0.42) | PTGS1AKR1C3AKR1C2CYP1A2KDM4E | |
| SCHEMBL8758020 | 0.79 | PTGS2 (0.46) | PTGS1AKR1C3AKR1C2CYP1A2KDM4E | |
| SCHEMBL3807329 | 0.79 | AKR1C3 (0.53) | PTGS1AKR1C3AKR1C2CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115960480-B | Light response self-repairing material containing thymine derivative and application thereof | 合肥工业大学 | 2023-09-12 | — | — | CN | claimed |
| CN-115960480-B | Light response self-repairing material containing thymine derivative and application thereof | 合肥工业大学 | 2023-09-12 | — | — | CN | disclosed |
| WO-2016114722-A1 | ALPHA-CELL SELECTIVE PROBE FOR EX-VIVO TWO PHOTON IMAGING OF ALPHA CELLS IN INTACT PANCREATIC ISLETS | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2016-07-21 | — | — | WO | disclosed |
| US-20150183737-A1 | COMPOSITIONS AND METHODS FOR SUBSTRATE-SELECTIVE INHIBITION OF ENDOCANNABINOID OXYGENATION | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2015-07-02 | — | — | US | disclosed |
| WO-2014015341-A2 | COMPOSITIONS AND METHODS FOR SUBSTRATE-SELECTIVE INHIBITION OF ENDOCANNABINOID OXYGENATION | VANDERBILT UNIVERSITY (US) | 2014-01-23 | — | — | WO | disclosed |
| US-20110065634-A1 | GLUCAGON RECEPTOR ANTAGONISTS, COMPOSITIONS, AND METHODS FOR THEIR USE | MERCK SHARP & DOHME LLC | 2011-03-17 | — | — | US | disclosed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010009215-A1 | NICOTINIC ACID RECEPTOR AGONIST COMPOUNDS USEFUL TO TREAT METABOLIC SYNDROMES | SCHERING CORPORATION (US) | 2010-01-21 | — | — | WO | disclosed |
| EP-1794138-A2 | THIAZOLO-NAPHTHYL ACIDS AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR-1 | Wyeth (US) | 2007-06-13 | — | — | EP | disclosed |
| EP-1781641-A1 | PYRROLO-NAPHTHYL ACIDS AS PAI-1 INHIBITORS | Wyeth (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2005040337-A2 | METHODS FOR BINDING AGENTS TO β-AMYLOID PLAQUES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-05-06 | — | — | WO | disclosed |
| EP-0221677-B1 | P-AMINOPHENOLS, DERIVATIVES THEREOF AND USE FOR MANUFACTURE OF A MEDICAMENT | E.R. Squibb & Sons, Inc. (US) | 1992-09-09 | — | — | EP | disclosed |
| EP-0176142-B1 | PROCESS FOR THE PREPARATION OF ARYL ALKYL KETONES | Nobel Chemicals AB (SE) | 1991-11-27 | — | — | EP | disclosed |
| US-4670603-A | Process for the preparation of aryl alkyl ketones | BLASCHIM S.P.A. (IT) | 1987-06-02 | — | — | US | disclosed |
| EP-0221677-A2 | p-Aminophenols, derivatives thereof and use for manufacture of a medicament | E.R. Squibb & Sons, Inc. (US) | 1987-05-13 | — | — | EP | disclosed |
| EP-0176142-A2 | Process for the preparation of aryl alkyl ketones | Nobel Chemicals AB (SE) | 1986-04-02 | — | — | EP | disclosed |
| US-4045485-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC AND ANTIPRURITIC ACTIVITY | SYNTEX CORPORATION (US) | 1977-08-30 | — | — | US | disclosed |
| US-3960936-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, SKIN DISORDERS | SYNTEX CORPORATION (PM) | 1976-06-01 | — | — | US | disclosed |
| US-3947472-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTIPRURITIC | SYNTEX CORPORATION (PM) | 1976-03-30 | — | — | US | disclosed |
| US-3935273-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTIPRURITIC | SYNTEX CORPORATION (US) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150183737-A1 | COMPOSITIONS AND METHODS FOR SUBSTRATE-SELECTIVE INHIBITION OF ENDOCANNABINOID OXYGENATION | CNR2, FAAH2, FAAH | PTGS1 24/4885AKR1C3 729/4885AKR1C2 821/4885 |
| US-20110065634-A1 | GLUCAGON RECEPTOR ANTAGONISTS, COMPOSITIONS, AND METHODS FOR THEIR USE | GLP1R, GCGR, GIPR | PTGS1 705/4885AKR1C3 223/4885AKR1C2 314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.