Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | IKBKB | O14920 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL2026072 | 0.94 | MMP2 (0.68) | MMP2ALDH1A1KDM4EMAPTHSD17B10 | |
| Cadaverine Tartrate SCHEMBL2021423 | 0.87 | MMP2 (0.59) | MMP2ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL698742 | 0.85 | KDM4E (0.61) | MMP2ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL720049 | 0.84 | MMP2 (0.72) | MMP2ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL3723645 | 0.83 | KDM4E (0.58) | MMP2ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL29547161 | 0.82 | MMP2 (1.00) | MMP2ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL204392 | 0.82 | MMP2 (1.00) | MMP2ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL3378787 | 0.80 | MMP2 (0.67) | MMP2ALDH1A1KDM4EMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL5110306 | 0.80 | MMP2 (0.96) | MMP2ALDH1A1KDM4EMAPTHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL1224587 | 0.80 | MMP2 (0.96) | MMP2ALDH1A1KDM4EMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8519168-B2 | Process and intermediates for the synthesis of 1,2-substituted 3,4-dioxo-1-cyclobutene compounds | MERCK SHARP & DOHME CORP. (US) | 2013-08-27 | — | — | US | claimed |
| US-20110160469-A1 | PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF 1,2-SUBSTITUTED 3,4-DIOXO-1-CYCLOBUTENE COMPOUNDS | MERCK SHARP & DOHME LLC | 2011-06-30 | — | — | US | claimed |
| CN-101932553-A | Process and intermediates for the synthesis of 1,2-substituted 3,4-dioxo-1-cyclobutene compounds | SCHERING CORP | 2010-12-29 | — | — | CN | claimed |
| EP-2178826-A1 | PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF 1,2-SUBSTITUTED 3,4-DIOXO-1-CYCLOBUTENE COMPOUNDS | SCHERING CORPORATION (US) | 2010-04-28 | — | — | EP | claimed |
| WO-2009005801-A1 | PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF 1,2-SUBSTITUTED 3,4-DIOXO-1-CYCLOBUTENE COMPOUNDS | SCHERING CORPORATION (US) | 2009-01-08 | — | — | WO | claimed |
| EP-0970057-B1 | SUBSTITUTED AMINOSALICYCLIC ACID AMIDES WITH FUNGICIDAL EFFECT AND INTERMEDIATE PRODUCTS FOR PRODUCTION THEREOF | BAYER CROPSCIENCE AG (DE) | 2006-02-01 | — | — | EP | claimed |
| CN-1121393-C | Substituted aminosalicylamides having fungicidal action and intermediates for their preparation | BAYER AG (DE) | 2003-09-17 | — | — | CN | claimed |
| EP-0848700-B1 | ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-07-02 | — | — | EP | claimed |
| US-20020006958-A1 | Substituted aminosalicylic acid amides with fungicidal effect and intermediate products for production thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2002-01-17 | — | — | US | claimed |
| US-6333432-B1 | CONTROLLING PHYTOPATHOGENS | DOW AGROSCIENCES LLC | 2001-12-25 | — | — | US | claimed |
| EP-1035772-A4 | FUNGICIDAL COMPOSITIONS AND METHODS, AND COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | DOW AGROSCIENCES LLC (US) | 2001-03-28 | — | — | EP | claimed |
| US-6194418-B1 | Substituted aminosalicyclic acid amides with fungicidal effect and intermediate products for production thereof | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-27 | — | — | US | claimed |
| EP-1035772-A1 | FUNGICIDAL COMPOSITIONS AND METHODS, AND COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | Dow AgroSciences LLC (US) | 2000-09-20 | — | — | EP | claimed |
| CN-1250442-A | Substituted aminosalicylamides having fungicidal action and intermediates for their preparation | BAYER AG (DE) | 2000-04-12 | — | — | CN | claimed |
| US-6001879-A | SUITABLE FOR CONTROLLING PESTS, PREFERABLY FUNGI, INSECTS AND BACTERIA, IN PLANTS AND INDUSTRIAL MATERIALS; METHODS OF THEIR SYBNTHESIS INCLUDING REACTING AMINOSALICYLAMIDES WITH ACYLATING AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-14 | — | — | US | claimed |
| WO-1999027783-A1 | FUNGICIDAL COMPOSITIONS AND METHODS, AND COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | DOW AGROSCIENCES LLC (US) | 1999-06-10 | — | — | WO | claimed |
| US-12454507-B2 | Compounds having a fungicidal activity, their agronomic compositions and use thereof for the control of phytopathogenic fungi | ISAGRO SPA (IT) | 2025-10-28 | — | — | US | disclosed |
| US-20240116855-A1 | COMPOUNDS HAVING A FUNGICIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF FOR THE CONTROL OF PHYTOPATHOGENIC FUNGI | ISAGRO S.P.A. (IT) | 2024-04-11 | — | — | US | disclosed |
| US-5648470-A | Phenylboronic acid complexing reagents derived from aminosalicyclic acid | PROLINX, INC. (US) | 1997-07-15 | — | — | US | disclosed |
| US-5382502-A | Photography, simplified synthesis | EASTMAN KODAK COMPANY (US) | 1995-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116855-A1 | COMPOUNDS HAVING A FUNGICIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF FOR THE CONTROL OF PHYTOPATHOGENIC FUNGI | CYP51A1, ERG28, DPM1 | MMP2 724/4885ALDH1A1 771/4885KDM4E 1149/4885 |
| US-20110160469-A1 | PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF 1,2-SUBSTITUTED 3,4-DIOXO-1-CYCLOBUTENE COMPOUNDS | CCL2, CCR1, CXCR1 | MMP2 2261/4885ALDH1A1 1721/4885KDM4E 4463/4885 |
| US-20020006958-A1 | Substituted aminosalicylic acid amides with fungicidal effect and intermediate products for production thereof | AADAC, DDC, DAO | MMP2 1072/4885ALDH1A1 353/4885KDM4E 1414/4885 |
| US-12454507-B2 | Compounds having a fungicidal activity, their agronomic compositions and use thereof for the control of phytopathogenic fungi | CYP51A1, ERG28, DPM1 | MMP2 724/4885ALDH1A1 771/4885KDM4E 1149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.