Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727774 | 0.81 | ALDH1A1 (0.54) | IDO1ALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL3723688 | 0.79 | ALDH1A1 (0.63) | ALDH1A1HPGDHSD17B10POLBHTT | |
| SCHEMBL3737263 | 0.77 | RAB9A (0.53) | IDO1ALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL11751335 | 0.73 | ALDH1A1 (0.52) | ALDH1A1HPGDHSD17B10POLBHTT | |
| SCHEMBL602492 | 0.72 | ALDH1A1 (0.69) | ALDH1A1HPGDPOLBHTTLMNA | |
| SCHEMBL3729996 | 0.71 | ALDH1A1 (0.73) | ALDH1A1HPGDHSD17B10ALOX15CRHBP | |
| SCHEMBL21384242 | 0.70 | ALDH1A1 (0.65) | IDO1ALDH1A1HPGDPOLBHTT | |
| SCHEMBL28654144 | 0.69 | ALDH1A1 (0.59) | ALDH1A1HPGDPOLBHTTLMNA | |
| SCHEMBL109671 | 0.69 | IDO1 (0.65) | IDO1DHFRHDAC3HDAC1HDAC2 | |
| SCHEMBL3726222 | 0.69 | ALDH1A1 (0.50) | ALDH1A1HPGDHSD17B10POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | BOUILLOT ANNE MARIE JEANNE | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | SCD, SCD5, FADS2 | IDO1 823/4885ALDH1A1 458/4885HPGD 203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.