Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3729134 | 0.85 | MAPT (0.57) | RAB9ANPC1SMN1; SMN2LMNAPKM | |
| SCHEMBL3729659 | 0.83 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2LMNAPKM | |
| SCHEMBL3728504 | 0.81 | ALDH1A1 (0.56) | RAB9ANPC1SMN1; SMN2LMNAPKM | |
| SCHEMBL3728220 | 0.78 | ALDH1A1 (0.52) | RAB9ANPC1SMN1; SMN2LMNAPKM | |
| SCHEMBL3727611 | 0.78 | MAPT (0.55) | RAB9ANPC1SMN1; SMN2LMNAPKM | |
| SCHEMBL3723669 | 0.77 | IDO1 (0.51) | LMNAPKMHSD17B10ALDH1A1HPGD | |
| SCHEMBL3726140 | 0.75 | LMNA (0.62) | RAB9ANPC1SMN1; SMN2LMNAPKM | |
| SCHEMBL3736372 | 0.75 | MAPT (0.61) | RAB9ANPC1SMN1; SMN2LMNAPKM | |
| SCHEMBL3733443 | 0.74 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2LMNAPKM | |
| SCHEMBL3729506 | 0.73 | LMNA (0.62) | RAB9ANPC1SMN1; SMN2LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | BOUILLOT ANNE MARIE JEANNE | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | SCD, SCD5, FADS2 | RAB9A 3330/4885NPC1 416/4885SMN1; SMN2 2732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.