Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | CKS1B | P61024 | 1/20 | 0.45 |
| ▸ | SKP1 | P63208 | 1/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722147 | 0.82 | DRD2 (0.46) | NQO2CKS1BSKP1SKP2IDO1 | |
| SCHEMBL3724621 | 0.79 | CKS1B (0.44) | NQO2CKS1BSKP1SKP2IDO1 | |
| SCHEMBL31393816 | 0.76 | TDP1 (0.45) | CKS1BSKP1SKP2ALDH1A1IDO1 | |
| SCHEMBL15283620 | 0.74 | CKS1B (0.50) | NQO2CKS1BSKP1SKP2CTSS | |
| SCHEMBL29695238 | 0.74 | NQO2 (0.50) | NQO2CKS1BSKP1SKP2CTSS | |
| SCHEMBL1579453 | 0.73 | NQO2 (0.75) | NQO2CTSSCTSKKDM4A | |
| Hydrochloric Acid SCHEMBL3722949 | 0.72 | MMP9 (0.50) | MMP9ALDH1A1L3MBTL1KMT2ARAB9A | |
| SCHEMBL4832420 | 0.72 | KEAP1 (0.44) | MMP9CTSSCTSKALDH1A1L3MBTL1 | |
| SCHEMBL23649248 | 0.71 | NQO2 (0.65) | NQO2CTSSCTSKKDM4A | |
| SCHEMBL15189256 | 0.71 | NPC1 (0.52) | CKS1BSKP1SKP2ALDH1A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010125103-A1 | DIKETOPIPERAZINE DERIVATIVES AS P2X7 MODULATORS | GLAXO GROUP LIMITED (GB) | 2010-11-04 | — | — | WO | disclosed |