Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.92 |
| ▸ | HTT | P42858 | 1/20 | 0.92 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.60 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5560406 | 0.96 | ALDH1A1 (1.00) | ALDH1A1HTTTSHRL3MBTL1MAPK1 | |
| SCHEMBL2706429 | 0.85 | ALDH1A1 (0.68) | ALDH1A1HTTTSHRPOLBKDM4E | |
| SCHEMBL696505 | 0.85 | ALDH1A1 (0.68) | ALDH1A1HTTTSHRL3MBTL1MAPK1 | |
| SCHEMBL2706426 | 0.85 | ALDH1A1 (0.68) | ALDH1A1HTTTSHRPOLBKDM4E | |
| SCHEMBL696506 | 0.85 | ALDH1A1 (0.68) | ALDH1A1HTTTSHRL3MBTL1MAPK1 | |
| SCHEMBL2636629 | 0.85 | ALDH1A1 (0.68) | ALDH1A1HTTTSHRL3MBTL1MAPK1 | |
| SCHEMBL31087000 | 0.85 | MAPK1 (0.71) | ALDH1A1HTTTSHRL3MBTL1MAPK1 | |
| Water SCHEMBL5497101 | 0.84 | ALDH1A1 (0.67) | ALDH1A1HTTTSHRL3MBTL1MAPK1 | |
| Hydrochloric Acid SCHEMBL4077465 | 0.84 | ALDH1A1 (0.67) | ALDH1A1HTTTSHRL3MBTL1MAPK1 | |
| Hydrochloric Acid SCHEMBL4077466 | 0.84 | ALDH1A1 (0.67) | ALDH1A1HTTTSHRL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8614201-B2 | Heterocyclic amides as modulators of TRPA1 | JANSSEN PHARMACEUTICA NV (BE) | 2013-12-24 | — | — | US | claimed |
| WO-2010141805-A1 | HETEROCYCLIC AMIDES AS MODULATORS OF TRPA1 | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-09 | — | — | WO | claimed |
| US-20260144730-A1 | COMPOSITION FOR SKIN ANTI-AGING, SKIN BRIGHTENING OR SKIN REVERSE-AGING CONTAINING AMIDE-BASED COMPOUND | AMOREPACIFIC CORPORATION (KR) | 2026-05-28 | — | — | US | disclosed |
| US-20260083715-A1 | COMPOSITION FOR ENHANCING IMMUNITY CONTAINING AMIDE-BASED COMPOUND | AMOREPACIFIC CORPORATION (KR) | 2026-03-26 | — | — | US | disclosed |
| EP-4692062-A1 | NOVEL AMIDE-BASED COMPOUND AND COMPOSITION COMPRISING SAME | Amorepacific Corporation (KR) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024205303-A1 | NOVEL AMIDE-BASED COMPOUND AND COMPOSITION COMPRISING SAME | (주)아모레퍼시픽 | 2024-10-03 | — | — | WO | disclosed |
| US-8614201-B2 | Heterocyclic amides as modulators of TRPA1 | JANSSEN PHARMACEUTICA NV (BE) | 2013-12-24 | — | — | US | disclosed |
| WO-2010141805-A1 | HETEROCYCLIC AMIDES AS MODULATORS OF TRPA1 | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260144730-A1 | COMPOSITION FOR SKIN ANTI-AGING, SKIN BRIGHTENING OR SKIN REVERSE-AGING CONTAINING AMIDE-BASED COMPOUND | TYR, ATG13, ARGLU1 | ALDH1A1 1443/4885HTT 1805/4885TSHR 3528/4885 |
| US-20260083715-A1 | COMPOSITION FOR ENHANCING IMMUNITY CONTAINING AMIDE-BASED COMPOUND | ARG1, MSR1, TLR1 | ALDH1A1 3501/4885HTT 4042/4885TSHR 2921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.