Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13076357 | 0.84 | ACACB (0.47) | ACACBCYP3A4CYP2C9ACACA | |
| SCHEMBL3724232 | 0.84 | PDE4B (0.46) | ACACBCYP3A4CYP2C9ACACAPDE4B | |
| SCHEMBL3722666 | 0.81 | MAOA (0.37) | ACACBCYP3A4CYP2C9ACACAMAPT | |
| SCHEMBL3721926 | 0.80 | PDE4B (0.44) | ACACBCYP3A4CYP2C9ACACAPDE4B | |
| SCHEMBL3724233 | 0.78 | ACACB (0.37) | ACACBCYP3A4CYP2C9ACACAMCHR1 | |
| SCHEMBL13077252 | 0.78 | ACACB (0.46) | ACACBCYP3A4CYP2C9ACACA | |
| SCHEMBL3720529 | 0.76 | ACACB (0.37) | ACACBCYP3A4CYP2C9ACACAMCHR1 | |
| SCHEMBL3718624 | 0.76 | ACACB (0.46) | ACACBCYP3A4CYP2C9ACACAMAPT | |
| SCHEMBL3721287 | 0.75 | ACACA (0.51) | ACACBCYP3A4CYP2C9ACACA | |
| SCHEMBL3721288 | 0.75 | MTNR1A (0.45) | MTNR1AACACBCYP3A4CYP2C9ACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |