SCHEMBL372452

SCHEMBL372452

CCCCn1cc(C)[n+](C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.42
RAB9A P51151 7/20 0.42
HTT P42858 6/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
KMT2A Q03164 3/20 0.42
HSP90AA1 P07900 3/20 0.42
MAPK1 P28482 3/20 0.42
NPSR1 Q6W5P4 3/20 0.42
MEN1 O00255 2/20 0.42
MAPT P10636 2/20 0.42
APAF1 O14727 1/20 0.42
PLA2G1B P04054 1/20 0.42
ATG4B Q9Y4P1 1/20 0.42
POLB P06746 3/20 0.32
LMNA P02545 3/20 0.32
ALDH1A1 P00352 2/20 0.32
APOBEC3A P31941 2/20 0.32
APOBEC3G Q9HC16 2/20 0.32
PABPC1 P11940 1/20 0.32
TYR P14679 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17131205 0.94 NPC1 (0.49) NPC1RAB9AHTTSMN1; SMN2KMT2A
SCHEMBL17131207 0.92 NPC1 (0.51) NPC1RAB9AHTTSMN1; SMN2KMT2A
SCHEMBL372850 0.88 MEN1 (0.32) NPC1RAB9AHTTSMN1; SMN2KMT2A
SCHEMBL17706424 0.78 NPC1 (0.41) NPC1RAB9AHTTSMN1; SMN2KMT2A
Hydrochloric Acid SCHEMBL30980118 0.77 POLB (0.34) NPC1RAB9AHTTSMN1; SMN2KMT2A
SCHEMBL17706421 0.77 NPC1 (0.40) NPC1RAB9AHTTSMN1; SMN2KMT2A
Hydrochloric Acid SCHEMBL30980116 0.77
Hydrochloric Acid SCHEMBL30980141 0.76 KMT2A (0.33) NPC1RAB9AHTTSMN1; SMN2KMT2A
Hydrochloric Acid SCHEMBL30980128 0.76 NPC1 (0.39) NPC1RAB9AHTTSMN1; SMN2KMT2A
SCHEMBL17706422 0.76 MEN1 (0.39) NPC1RAB9AHTTSMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3512905-B1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2022-08-24 EP claimed
US-11377535-B2 Carbon fiber recovery compositions and methods THE BOEING COMPANY (US) 2022-07-05 US claimed
EP-3762447-A1 METHOD FOR PRODUCING FIBRES, FILMS AND MOULDED BODIES OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2021-01-13 EP claimed
US-20200407508-A1 METHOD FOR PRODUCING FIBERS, FILMS AND MOLDINGS OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2020-12-31 US claimed
US-20200207940-A1 Carbon Fiber Recovery Compositions and Methods THE BOEING COMPANY 2020-07-02 US claimed
WO-2019170529-A1 METHOD FOR PRODUCING FIBRES, FILMS AND MOULDED BODIES OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2019-09-12 WO claimed
EP-3512905-A1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2019-07-24 EP claimed
US-20180291174-A1 Carbon Fiber Recovery Compositions and Methods THE BOEING COMPANY 2018-10-11 US claimed
WO-2018050489-A1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2018-03-22 WO claimed
EP-1984438-B2 ANTISTATIC POLYURETHANE BASF SE (DE) 2016-05-18 EP claimed
US-20090300946-A1 ANTISTATIC POLYURETHANE BASF SE (DE) 2009-12-10 US claimed
EP-1789160-B1 METHOD FOR SEPARATING HYDROGEN CHLORIDE AND PHOSGENE BASF SE (DE) 2009-11-18 EP claimed
US-20090112017-A1 METHOD FOR PRODUCING POLYISOCYANATES BASF AKTIENGESSELLSCHAFT (DE) 2009-04-30 US claimed
EP-1984438-A1 ANTISTATIC POLYURETHANE BASF SE (DE) 2008-10-29 EP claimed
US-20070293707-A1 Method for Separating Hydrogen Chloride and Phosgene BASF AKTIENGESELLSCHAFT (DE) 2007-12-20 US claimed
WO-2007090755-A1 ANTISTATIC POLYURETHANE BASF AKTIENGESELLSCHAFT (DE) 2007-08-16 WO claimed
EP-1812382-A1 METHOD FOR PRODUCING POLYISOCYANATES BASF AKTIENGESELLSCHAFT (DE) 2007-08-01 EP claimed
EP-1789160-A1 METHOD FOR SEPARATING HYDROGEN CHLORIDE AND PHOSGENE BASF AKTIENGESELLSCHAFT (DE) 2007-05-30 EP claimed
WO-2006048171-A1 METHOD FOR PRODUCING POLYISOCYANATES BASF AKTIENGESELLSCHAFT (DE) 2006-05-11 WO claimed
WO-2006029788-A1 METHOD FOR SEPARATING HYDROGEN CHLORIDE AND PHOSGENE BASF AKTIENGESELLSCHAFT (DE) 2006-03-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090112017-A1 METHOD FOR PRODUCING POLYISOCYANATES PGLS, INMT, PNMT NPC1 1697/4885RAB9A 3609/4885HTT 1805/4885
US-20070293707-A1 Method for Separating Hydrogen Chloride and Phosgene PSPH, SLC9B2, HVCN1 NPC1 2934/4885RAB9A 2053/4885HTT 569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.