Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.59 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | ACACA | Q13085 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727069 | 0.90 | MTNR1A (0.62) | ACACBMTNR1AMTNR1BSMN1; SMN2SCN9A | |
| SCHEMBL3726818 | 0.86 | ACACB (0.64) | ACACBMTNR1AMTNR1BSMN1; SMN2KDM4E | |
| SCHEMBL3720307 | 0.83 | MTNR1A (0.61) | ACACBMTNR1AMTNR1BSMN1; SMN2ACACA | |
| SCHEMBL3724679 | 0.80 | ACACB (0.51) | ACACBMTNR1AMTNR1BSMN1; SMN2ALDH1A1 | |
| SCHEMBL3722415 | 0.80 | ACACB (0.51) | ACACBMTNR1AMTNR1BSMN1; SMN2KDM4E | |
| SCHEMBL3720261 | 0.80 | ACACB (0.51) | ACACBMTNR1AMTNR1BSMN1; SMN2KDM4E | |
| SCHEMBL3717125 | 0.80 | MTNR1A (0.64) | ACACBMTNR1AMTNR1BSMN1; SMN2SCN9A | |
| SCHEMBL3726453 | 0.78 | KDM4E (0.63) | ACACBMTNR1AMTNR1BSMN1; SMN2KDM4E | |
| SCHEMBL3720862 | 0.78 | ACACB (0.53) | ACACBMTNR1AMTNR1BSMN1; SMN2SCN9A | |
| SCHEMBL3721156 | 0.78 | MTNR1A (0.55) | ACACBMTNR1AMTNR1BSMN1; SMN2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |