Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9888805 | 0.92 | TSHR (0.79) | TSHRL3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL25778887 | 0.89 | TSHR (0.69) | TSHRL3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL3727479 | 0.86 | TSHR (0.87) | TSHRL3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL23189063 | 0.86 | KDM4E (0.53) | TSHRL3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL27535566 | 0.85 | MCL1 (0.53) | TSHRL3MBTL1ALDH1A1KDM4ELMNA | |
| SCHEMBL10359783 | 0.83 | PPARG (0.67) | TSHRL3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL6897570 | 0.83 | MRGPRX4 (0.53) | TSHRL3MBTL1KDM4ELMNAFFAR4 | |
| SCHEMBL7523915 | 0.83 | TSHR (0.58) | TSHRL3MBTL1ALDH1A1KDM4ENPC1 | |
| SCHEMBL3667070 | 0.83 | KDM4E (0.65) | TSHRALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL23268917 | 0.83 | LMNA (0.66) | TSHRL3MBTL1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2053918-B1 | PROPYL PHENOXY ETHERS FOR USE AS DELIVERY AGENTS | EMISPHERE TECH INC (US) | 2014-07-23 | — | — | EP | disclosed |
| EP-2053918-B1 | PROPYL PHENOXY ETHERS FOR USE AS DELIVERY AGENTS | EMISPHERE TECH INC (US) | 2014-07-23 | — | — | EP | disclosed |
| US-20100062970-A1 | SYNTHESIS OF PROPYL PHENOXY ETHERS AND USE AS DELIVERY AGENTS | EMISPHERE TECHNOLOGIES INC. (US) | 2010-03-11 | — | — | US | disclosed |
| US-20100062970-A1 | SYNTHESIS OF PROPYL PHENOXY ETHERS AND USE AS DELIVERY AGENTS | EMISPHERE TECHNOLOGIES INC. (US) | 2010-03-11 | — | — | US | disclosed |
| US-20100062970-A1 | SYNTHESIS OF PROPYL PHENOXY ETHERS AND USE AS DELIVERY AGENTS | EMISPHERE TECHNOLOGIES INC. (US) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100062970-A1 | SYNTHESIS OF PROPYL PHENOXY ETHERS AND USE AS DELIVERY AGENTS | EPX, HPD, CYP2C8 | TSHR 3844/4885L3MBTL1 3481/4885ALDH1A1 3161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.