Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 4/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826039 | 0.88 | MAPT (0.56) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL30344595 | 0.84 | ALDH1A1 (0.49) | ALDH1A1TSHRCYP3A4RECQLMAPT | |
| SCHEMBL21333726 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNAAR | |
| SCHEMBL10974505 | 0.83 | KDM4E (0.50) | ALDH1A1MAPTNPSR1LMNACYP2C9 | |
| SCHEMBL9527470 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP3A4MAPTMEN1 | |
| SCHEMBL3721960 | 0.81 | MAPT (0.64) | ALDH1A1TSHRCYP3A4RECQLMAPT | |
| SCHEMBL1494443 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TSHRCYP3A4RECQLMAPT | |
| SCHEMBL10270453 | 0.80 | KDM4E (0.47) | ALDH1A1RECQLMAPTLMNAAR | |
| SCHEMBL4636442 | 0.80 | ATM (0.50) | ALDH1A1MAPTLMNAAR | |
| SCHEMBL31714528 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP3A4RECQLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127212-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |
| US-20100280067-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | SARMA PAKALA KUMARA SAVITHRU | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280067-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | ACACA, ACACB, PC | ALDH1A1 276/4885TSHR 4536/4885CYP3A4 1491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.