Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2778087 | 0.83 | GAA (0.44) | GAAKMT2AMAPTMAPK1TDP1 | |
| SCHEMBL3763682 | 0.82 | DRD2 (0.58) | DRD2DRD4DRD3RAB9ANPC1 | |
| SCHEMBL18560985 | 0.81 | L3MBTL1 (0.53) | GAADRD2DRD4DRD3RAB9A | |
| SCHEMBL17637581 | 0.80 | DRD2 (0.61) | DRD2DRD4DRD3RAB9ANPC1 | |
| SCHEMBL11767977 | 0.80 | GAA (0.68) | GAAKMT2AMAPTALDH1A1 | |
| SCHEMBL10745573 | 0.79 | GAA (0.58) | GAADRD2DRD4DRD3NPC1 | |
| SCHEMBL3728565 | 0.76 | KMT2A (0.52) | DRD2DRD4DRD3RAB9AKMT2A | |
| SCHEMBL469900 | 0.76 | DRD2 (0.53) | DRD2DRD4DRD3RAB9ANPC1 | |
| SCHEMBL15760678 | 0.76 | KDM4E (0.53) | DRD2DRD4DRD3RAB9ANPC1 | |
| SCHEMBL11764164 | 0.76 | GAA (0.50) | GAAMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2053918-B1 | PROPYL PHENOXY ETHERS FOR USE AS DELIVERY AGENTS | EMISPHERE TECH INC (US) | 2014-07-23 | — | — | EP | disclosed |
| US-20100062970-A1 | SYNTHESIS OF PROPYL PHENOXY ETHERS AND USE AS DELIVERY AGENTS | EMISPHERE TECHNOLOGIES INC. (US) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100062970-A1 | SYNTHESIS OF PROPYL PHENOXY ETHERS AND USE AS DELIVERY AGENTS | EPX, HPD, CYP2C8 | GAA 3574/4885DRD2 2188/4885DRD4 1239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.