Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL120830 | 0.80 | ALDH1A1 (0.46) | CYP1A2NCF1HTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL29443135 | 0.80 | ALDH1A1 (0.46) | CYP1A2NCF1HTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL3975907 | 0.78 | CYP1A2 (0.58) | CYP1A2NCF1HTTMEN1KMT2A | |
| SCHEMBL6824379 | 0.78 | HTT (0.54) | CYP1A2NCF1HTTMEN1KMT2A | |
| SCHEMBL29877118 | 0.76 | LMNA (0.64) | CYP1A2NCF1HTTMEN1KMT2A | |
| SCHEMBL266444 | 0.76 | LMNA (0.64) | CYP1A2NCF1HTTMEN1KMT2A | |
| SCHEMBL25490903 | 0.75 | NCF1 (0.59) | CYP1A2NCF1HTTMEN1KMT2A | |
| SCHEMBL7532440 | 0.73 | CYP1A2 (0.56) | CYP1A2NCF1HTTMEN1KMT2A | |
| SCHEMBL11554023 | 0.73 | NCEH1 (0.55) | CYP1A2HTTMEN1KMT2AL3MBTL1 | |
| SCHEMBL423902 | 0.72 | CYP1A2 (0.55) | CYP1A2NCF1GAASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168030-A1 | Methods and compositions for treatment of organophosphate-caused pathology | ARMY, UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE | 2010-07-01 | — | — | US | disclosed |