Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716760 | 0.91 | KMT2A (0.55) | ACACBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL3722470 | 0.90 | MAPT (0.51) | ACACBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL3727563 | 0.82 | ACACB (0.50) | ACACBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL3723896 | 0.82 | GLA (0.59) | ACACBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL3726818 | 0.79 | ACACB (0.64) | ACACBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL3726437 | 0.78 | ACACB (0.65) | ACACBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL3721222 | 0.78 | CES2 (0.50) | ACACBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL3723856 | 0.77 | LTA4H (0.49) | SMN1; SMN2LTA4HPLA2G2AGLALMNA | |
| SCHEMBL3240006 | 0.76 | CES2 (0.66) | MAPTNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL3724136 | 0.76 | ACACB (0.57) | ACACBMAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |