Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3729970 | 0.98 | KEAP1 (0.59) | KEAP1MAPK1GAANPC1L3MBTL1 | |
| SCHEMBL3725948 | 0.98 | KEAP1 (0.59) | KEAP1MAPK1GAANPC1L3MBTL1 | |
| SCHEMBL26219177 | 0.84 | MAPK1 (0.70) | KEAP1MAPK1GAANPC1L3MBTL1 | |
| SCHEMBL27934132 | 0.81 | MAPK1 (0.74) | KEAP1MAPK1GAANPC1L3MBTL1 | |
| SCHEMBL16752537 | 0.79 | ADRB1 (0.64) | ALDH1A1MAPTKDM4ETSHRHSD17B10 | |
| SCHEMBL28282917 | 0.79 | GAA (0.50) | KEAP1MAPK1GAANPC1L3MBTL1 | |
| SCHEMBL4423797 | 0.76 | MAPK1 (0.60) | KEAP1MAPK1GAANPC1L3MBTL1 | |
| SCHEMBL1825806 | 0.75 | ADRB1 (0.65) | KEAP1MAPK1GAAL3MBTL1ALDH1A1 | |
| SCHEMBL945417 | 0.75 | GAA (0.50) | KEAP1MAPK1GAANPC1L3MBTL1 | |
| SCHEMBL484010 | 0.73 | KEAP1 (0.95) | KEAP1MAPK1GAANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080161519-A1 | Catalyst System for Synthesizing Amine Functionalized Rubbery Polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2008-07-03 | — | — | US | claimed |
| EP-1939224-A1 | Catalyst system for synthesizing amine functionalized rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2008-07-02 | — | — | EP | claimed |
| US-7825203-B2 | Catalyst system for synthesizing amine functionalized rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2010-11-02 | — | — | US | disclosed |
| US-20080161519-A1 | Catalyst System for Synthesizing Amine Functionalized Rubbery Polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2008-07-03 | — | — | US | disclosed |
| EP-1939224-A1 | Catalyst system for synthesizing amine functionalized rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2008-07-02 | — | — | EP | disclosed |