Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NCF1 | P14598 | 2/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3725948 | 1.00 | KEAP1 (0.59) | KEAP1MAPK1GAANPC1HPGD | |
| SCHEMBL3727593 | 0.98 | KEAP1 (0.56) | KEAP1MAPK1GAANPC1HPGD | |
| SCHEMBL27934132 | 0.85 | MAPK1 (0.74) | KEAP1MAPK1GAANPC1HPGD | |
| SCHEMBL26219177 | 0.82 | MAPK1 (0.70) | KEAP1MAPK1GAANPC1HPGD | |
| SCHEMBL28282917 | 0.81 | GAA (0.50) | KEAP1MAPK1GAANPC1L3MBTL1 | |
| SCHEMBL16752537 | 0.77 | ADRB1 (0.64) | HPGDMAPTALDH1A1NCF1KDM4E | |
| SCHEMBL10893618 | 0.76 | ADRB1 (0.63) | KEAP1MAPK1GAANPC1L3MBTL1 | |
| SCHEMBL9655124 | 0.76 | ADRB1 (0.63) | KEAP1MAPK1GAANPC1L3MBTL1 | |
| SCHEMBL3021427 | 0.74 | KEAP1 (0.57) | KEAP1MAPK1GAANPC1HPGD | |
| SCHEMBL73609 | 0.74 | KEAP1 (1.00) | KEAP1MAPK1GAANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825203-B2 | Catalyst system for synthesizing amine functionalized rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2010-11-02 | — | — | US | disclosed |
| US-20080161519-A1 | Catalyst System for Synthesizing Amine Functionalized Rubbery Polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2008-07-03 | — | — | US | disclosed |
| EP-1939224-A1 | Catalyst system for synthesizing amine functionalized rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2008-07-02 | — | — | EP | disclosed |