Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3638697 | 0.82 | BACE1 (0.48) | POLBALDH1A1HTTUSP2 | |
| SCHEMBL3635503 | 0.71 | HSD17B10 (0.43) | KMT2AKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL8028141 | 0.70 | ALDH1A1 (0.72) | KMT2AKDM4EPOLBALDH1A1MAPT | |
| SCHEMBL11840363 | 0.66 | MEN1 (0.43) | KMT2AKDM4EPOLBALDH1A1MAPT | |
| SCHEMBL15355424 | 0.66 | PRMT5 (0.67) | KMT2AMAPTHRH3MEN1 | |
| SCHEMBL1721447 | 0.66 | KIT (0.43) | KMT2AALDH1A1GAAHPGDTSHR | |
| Hydrochloric Acid SCHEMBL11840359 | 0.65 | MEN1 (0.43) | KMT2AKDM4EPOLBALDH1A1MAPT | |
| SCHEMBL24312147 | 0.65 | PRMT5 (0.46) | — | |
| SCHEMBL20135734 | 0.64 | MEN1 (0.61) | KMT2APOLBALDH1A1GAAHTT | |
| SCHEMBL7921315 | 0.64 | MEN1 (0.64) | KMT2AKDM4EPOLBALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167466-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | Glaxo Group Limited (GB) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008148853-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |