Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3635501 | 0.82 | SCD5 (0.48) | HSD17B10ALDH1A1HPGDNPC1LMNA | |
| SCHEMBL13984721 | 0.82 | KMT2A (0.45) | HSD17B10TSHRALDH1A1HPGDNPC1 | |
| SCHEMBL2847196 | 0.77 | NPC1 (0.44) | HSD17B10TSHRALDH1A1HPGDNPC1 | |
| SCHEMBL3637345 | 0.73 | MGLL (0.48) | TSHRALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL3727736 | 0.71 | KMT2A (0.41) | HSD17B10ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL20408678 | 0.68 | MGLL (0.51) | HSD17B10ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL4694192 | 0.66 | CRHBP (0.77) | ALDH1A1HPGDLMNAKDM4ECYP1A2 | |
| SCHEMBL4694193 | 0.66 | CRHBP (0.77) | ALDH1A1HPGDLMNAKDM4ECYP1A2 | |
| SCHEMBL11373237 | 0.66 | ALDH1A1 (0.44) | HSD17B10TSHRALDH1A1HPGDNPC1 | |
| SCHEMBL11373238 | 0.66 | ALDH1A1 (0.44) | HSD17B10TSHRALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167466-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | Glaxo Group Limited (GB) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008148853-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |