Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | TEC | P42680 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.33 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.32 |
| ▸ | TAAR5 | O14804 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719936 | 0.85 | MET (0.35) | METACHEBACE1SCN9ANAPEPLD | |
| SCHEMBL3720089 | 0.83 | TEC (0.37) | TEC | |
| SCHEMBL3720268 | 0.83 | KDM4E (0.36) | BACE1SCN9ALTA4H | |
| SCHEMBL3720365 | 0.80 | MAPT (0.41) | TECTAAR5TAAR1 | |
| SCHEMBL3719857 | 0.80 | ALDH1A1 (0.37) | — | |
| SCHEMBL3722383 | 0.79 | CYP1A2 (0.35) | TECSCN9ATAAR5TAAR1 | |
| SCHEMBL3717025 | 0.78 | PARP10 (0.40) | — | |
| Trifluoroacetic Acid SCHEMBL3802671 | 0.78 | MTNR1A (0.45) | SCN9A | |
| SCHEMBL3722576 | 0.78 | TLR8 (0.40) | TAAR5TAAR1 | |
| SCHEMBL3717202 | 0.77 | ACACB (0.38) | TECTAAR5TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |