Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3728071 | 0.85 | MET (0.33) | METLTA4HACHEBACE1SCN9A | |
| SCHEMBL3721863 | 0.84 | MAPT (0.39) | PDE4BP2RX3 | |
| SCHEMBL3719580 | 0.83 | ACACB (0.38) | — | |
| SCHEMBL3722548 | 0.83 | MAPT (0.36) | LTA4HSCN9AALOX5P2RX3 | |
| SCHEMBL3726251 | 0.79 | SCN9A (0.33) | SCN9AALOX5PDE4B | |
| SCHEMBL3722876 | 0.78 | ACACB (0.41) | ALOX5 | |
| SCHEMBL3717738 | 0.78 | TEC (0.39) | — | |
| SCHEMBL3726328 | 0.77 | ACACB (0.40) | — | |
| Trifluoroacetic Acid SCHEMBL3802671 | 0.76 | MTNR1A (0.45) | SCN9A | |
| SCHEMBL3720134 | 0.76 | ALDH1A1 (0.48) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |