Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 4/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28550353 | 0.82 | SMN1; SMN2 (0.39) | ALDH1A1MAPTLMNAARGPR3 | |
| SCHEMBL10974505 | 0.81 | KDM4E (0.50) | CYP2C9ALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL21333726 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNAKDM4EAR | |
| SCHEMBL3722104 | 0.81 | MAPT (0.59) | CYP2C19ALDH1A1MAPTLMNA | |
| SCHEMBL9527470 | 0.79 | ALDH1A1 (0.50) | CYP2C9ALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL3724718 | 0.79 | ALDH1A1 (0.46) | CYP17A1CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL6826071 | 0.79 | MAPT (0.43) | ALDH1A1MAPTLMNAKDM4EAR | |
| SCHEMBL10270453 | 0.78 | KDM4E (0.47) | CYP2C9ALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL4636442 | 0.78 | ATM (0.50) | ALDH1A1MAPTLMNAKDM4EAR | |
| SCHEMBL3723171 | 0.77 | CYP2C9 (0.43) | CYP17A1CYP2C9CYP2C19ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127212-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |
| US-20100280067-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | SARMA PAKALA KUMARA SAVITHRU | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280067-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | ACACA, ACACB, PC | CYP17A1 431/4885CYP2C9 1891/4885CYP2C19 2303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.