Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL601561 | 1.00 | MAOA (0.36) | MAOAMAOBCA12CA14CTSK | |
| SCHEMBL601562 | 1.00 | MAOA (0.36) | MAOAMAOBCA12CA14CTSK | |
| SCHEMBL3808762 | 0.86 | CRBN (0.34) | MAOAMAOBCTSKDGAT1 | |
| SCHEMBL3808765 | 0.86 | CRBN (0.34) | MAOAMAOBCTSKDGAT1 | |
| SCHEMBL18421858 | 0.85 | MAOA (0.36) | MAOAMAOBCA12CA14CTSK | |
| SCHEMBL4715528 | 0.85 | MAOA (0.36) | MAOAMAOBCA12CA14CTSK | |
| SCHEMBL14765111 | 0.85 | MAOA (0.36) | MAOAMAOBCA12CA14CTSK | |
| SCHEMBL15324528 | 0.83 | APLNR (0.40) | MAOAMAOBCA12CA14CTSK | |
| SCHEMBL6379683 | 0.80 | DGAT1 (0.34) | MAOAMAOBCTSKTDP1DGAT1 | |
| SCHEMBL3144118 | 0.80 | TDP1 (0.35) | CA12CA14NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025101904-A1 | NOREPINEPHRINE TRANSPORTER-TARGETED PRODRUGS FOR CANCER THERAPY | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2025-05-15 | — | — | WO | disclosed |
| US-12234229-B2 | Sphingosine kinase inhibitor amidoxime prodrugs | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2025-02-25 | — | — | US | disclosed |
| WO-2024123663-A1 | ANTIMICROBIAL COMPOUNDS | SRI INTERNATIONAL (US) | 2024-06-13 | — | — | WO | disclosed |
| CN-118047726-A | Ferulic acid ester analogues, preparation method and application thereof | 西北大学 | 2024-05-17 | — | — | CN | disclosed |
| EP-3189059-B1 | THIENOPYRROLES AS HISTONE DEMETHYLASE INHIBITORS | ST EUROPEO DI ONCOLOGIA S R L (IT) | 2023-02-22 | — | — | EP | disclosed |
| US-20230050649-A1 | SPHINGOSINE KINASE INHIBITOR AMIDOXIME PRODRUGS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2023-02-16 | — | — | US | disclosed |
| EP-3341007-B1 | MALT1 INHIBITORS AND USES THEREOF | UNIV CORNELL (US) | 2020-12-23 | — | — | EP | disclosed |
| US-10111437-B2 | Substituted guanidines as fungicides | NIPPON SODA CO., LTD. (JP) | 2018-10-30 | — | — | US | disclosed |
| US-20180146677-A1 | GUANICIDE COMPOUND AND FUNGICIDE | NIPPON SODA CO., LTD. (JP) | 2018-05-31 | — | — | US | disclosed |
| WO-2016156597-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN PREVENTING OR TREATING BACTERIAL INFECTIONS | MUTABILIS (FR) | 2016-10-06 | — | — | WO | disclosed |
| US-8110574-B2 | Derivatives of 4-aminopiperidine and their use as a medicament | IPSEN PHARMA S.A.S. (FR) | 2012-02-07 | — | — | US | disclosed |
| US-7935782-B2 | Multifunctional degradable nanoparticles with control over size and functionalities | VANDERBILT UNIVERSITY (US) | 2011-05-03 | — | — | US | disclosed |
| US-20110059971-A1 | DERIVATIVES OF 4-AMINOPIPERIDINE AND THEIR USE AS A MEDICAMENT | IPSEN S.A.S. (FR) | 2011-03-10 | — | — | US | disclosed |
| US-7858789-B2 | Derivatives of 4-aminopiperidine and their use as a medicament | IPSEN PHARMA S.A.S. (FR) | 2010-12-28 | — | — | US | disclosed |
| US-7825279-B2 | Fused ring dicationic anti-protozoan agents and their prodrugs | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2010-11-02 | — | — | US | disclosed |
| US-20090306335-A1 | MULTIFUNCTIONAL DEGRADABLE NANOPARTICLES WITH CONTROL OVER SIZE AND FUNCTIONALITIES | NATIONAL SCIENCE FOUNDATION | 2009-12-10 | — | — | US | disclosed |
| US-20090149652-A1 | Derivatives of 4-aminopiperidine and their use as a medicament | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES | 2009-06-11 | — | — | US | disclosed |
| US-20080221043-A1 | Guanidinium compounds for drug delivery | VANDERBILT UNIVERSITY | 2008-09-11 | — | — | US | disclosed |
| US-7393861-B2 | Derivatives of 4-aminopiperidine and their use as a medicament | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2008-07-01 | — | — | US | disclosed |
| US-20050165044-A1 | Fused ring dicationic anti-protozoan agents and their prodrugs | BOYKIN DAVID W (US) | 2005-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12234229-B2 | Sphingosine kinase inhibitor amidoxime prodrugs | SPHK1, SPHK2, S1PR2 | MAOA 2104/4885MAOB 1318/4885CA12 4019/4885 |
| US-20090149652-A1 | Derivatives of 4-aminopiperidine and their use as a medicament | SSTR4, SSTR3, SSTR1 | MAOA 890/4885MAOB 733/4885CA12 4153/4885 |
| US-20180146677-A1 | GUANICIDE COMPOUND AND FUNGICIDE | GUCY1A2, GUCY1B2, GUCY1A1 | MAOA 792/4885MAOB 826/4885CA12 4537/4885 |
| US-10111437-B2 | Substituted guanidines as fungicides | GUCY1A2, GUCY1B2, GUCY1A1 | MAOA 438/4885MAOB 630/4885CA12 4677/4885 |
| US-20230050649-A1 | SPHINGOSINE KINASE INHIBITOR AMIDOXIME PRODRUGS | SPHK1, SPHK2, S1PR2 | MAOA 2104/4885MAOB 1318/4885CA12 4019/4885 |
| US-20110059971-A1 | DERIVATIVES OF 4-AMINOPIPERIDINE AND THEIR USE AS A MEDICAMENT | SSTR4, SSTR3, SSTR1 | MAOA 890/4885MAOB 733/4885CA12 4153/4885 |
| US-20080221043-A1 | Guanidinium compounds for drug delivery | GMPS, GUCY1A1, GUCY1A2 | MAOA 889/4885MAOB 814/4885CA12 3576/4885 |
| US-20050165044-A1 | Fused ring dicationic anti-protozoan agents and their prodrugs | DHODH, DHFR, PAICS | MAOA 4456/4885MAOB 3612/4885CA12 4229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.