Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.35 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL943020 | 1.00 | RXRA (0.40) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL10850841 | 0.83 | RXRA (0.40) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL1008766 | 0.79 | RAPGEF3 (0.40) | HDAC3HDAC1HDAC2HDAC6RAPGEF3 | |
| SCHEMBL10776182 | 0.78 | RXRA (0.49) | RXRARXRBRXRGKMT2AMEN1 | |
| SCHEMBL586419 | 0.73 | AKR1C3 (0.54) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL10851034 | 0.72 | SMN1; SMN2 (0.38) | RAPGEF3RAPGEF4KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1056618 | 0.72 | CYP1A2 (0.48) | KMT2ALMNAHTTKDM4E | |
| SCHEMBL585795 | 0.71 | RXRA (0.43) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL10084735 | 0.71 | RXRA (0.40) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL7271607 | 0.70 | GRN (0.35) | RAPGEF3RAPGEF4AKR1C3AKR1C2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136145-A1 | PYRAZINYLPYRAZOLES | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | WO | disclosed |