Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31124636 | 0.72 | TSHR (0.45) | ALDH1A1SMN1; SMN2TDP1L3MBTL1LTA4H | |
| SCHEMBL73211 | 0.70 | CALM1 (0.46) | CALM1ALDH1A1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL158147 | 0.68 | ALDH1A1 (0.46) | CALM1ALDH1A1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL27072915 | 0.67 | CALM1 (0.55) | CALM1ALDH1A1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL11330543 | 0.67 | KCNH2 (0.62) | CALM1ALDH1A1RAB9ASMN1; SMN2TDP1 | |
| Diphenylmethane SCHEMBL4361124 | 0.66 | CALM1 (1.00) | CALM1ALDH1A1LMNALTA4HHPGD | |
| Diphenylmethane SCHEMBL3792579 | 0.66 | CALM1 (1.00) | CALM1ALDH1A1LMNALTA4HHPGD | |
| Diphenylmethane SCHEMBL28172316 | 0.66 | CALM1 (1.00) | CALM1ALDH1A1LMNALTA4HHPGD | |
| Diphenylmethane SCHEMBL14763944 | 0.66 | CALM1 (1.00) | CALM1ALDH1A1LMNALTA4HHPGD | |
| Diphenylmethane SCHEMBL1303 | 0.66 | CALM1 (1.00) | CALM1ALDH1A1LMNALTA4HHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2807161-A1 | TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES | Merck Patent GmbH (DE) | 2014-12-03 | — | — | EP | disclosed |
| WO-2013110309-A1 | TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2013-08-01 | — | — | WO | disclosed |
| US-20100158829-A1 | Method and Composition for Color Modulation | CONOPCO, INC., D/B/A UNILEVER (US) | 2010-06-24 | — | — | US | disclosed |
| EP-0861456-B1 | IMAGE-RECORDING MATERIALS | POLAROID CORP (US) | 2000-06-21 | — | — | EP | disclosed |
| US-5811530-A | MONOAZO CYAN DYE CHROMOPHOR HAVING A BENZOISOTHIAZOLE MOIETY, DIFFUSION CONTROL GROUP; FOR PEEL-APART PHOTOGRAPHIC FILMS | POLAROID CORPORATION (US) | 1998-09-22 | — | — | US | disclosed |
| EP-0861456-A1 | IMAGE-RECORDING MATERIALS | POLAROID CORPORATION (US) | 1998-09-02 | — | — | EP | disclosed |
| WO-1998012602-A1 | IMAGE-RECORDING MATERIALS | POLAROID CORPORATION (US) | 1998-03-26 | — | — | WO | disclosed |
| US-5716754-A | INCLUDING IMAGE DYE-PROVIDING COMPOUND COMPRISING NAPHTHOL AZO CYAN DYE HAVING 3-AMINOBENZISOTHIAZOLE MOIETY | POLAROID CORPORATION (US) | 1998-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158829-A1 | Method and Composition for Color Modulation | TYR, TH, COMT | CALM1 2560/4885ALDH1A1 2383/4885RAB9A 1023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.