SCHEMBL158147

SCHEMBL158147

c1ccc(Cc2csnn2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
CALM1 P0DP23 1/20 0.44
RAB9A P51151 4/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
MEN1 O00255 2/20 0.42
NPC1 O15118 2/20 0.42
KMT2A Q03164 2/20 0.42
POLB P06746 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MAOB P27338 1/20 0.39
HTR2C P28335 1/20 0.37
CD74 P04233 1/20 0.37
MIF P14174 1/20 0.37
LMNA P02545 1/20 0.36
LTA4H P09960 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
FYN P06241 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzenesulfonamide SCHEMBL3255610 0.84 CA1 (0.50) ALDH1A1
SCHEMBL11207065 0.71 MAOA (0.50) ALDH1A1RAB9ASMN1; SMN2MEN1NPC1
SCHEMBL3728814 0.68 CALM1 (0.46) ALDH1A1CALM1RAB9ASMN1; SMN2NPC1
SCHEMBL11428118 0.67 FABP1 (0.50) ALDH1A1SMN1; SMN2MEN1KMT2AL3MBTL1
SCHEMBL7533150 0.67 LTA4H (0.48) ALDH1A1CALM1RAB9ASMN1; SMN2NPC1
SCHEMBL10388633 0.66 MEN1 (0.52) RAB9ASMN1; SMN2MEN1NPC1KMT2A
SCHEMBL11330543 0.66 KCNH2 (0.62) ALDH1A1CALM1RAB9ASMN1; SMN2POLB
SCHEMBL27072915 0.66 CALM1 (0.55) ALDH1A1CALM1RAB9ASMN1; SMN2TDP1
SCHEMBL289429 0.66
SCHEMBL345263 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 895 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3726994-B1 BCA CONTROL OF STB DANSTAR FERMENT AG (CH) 2024-09-11 EP claimed
WO-2024140637-A1 OXOISOINDOLINYL SUBSTITUTED PIPERIDINEDIONE DERIVATIVE AND USE THEREOF 标新生物医药科技(上海)有限公司 2024-07-04 WO claimed
WO-2024051766-A1 MOLECULAR GLUE COMPOUND BASED ON CEREBLON PROTEIN DESIGN AND USE THEREOF 标新生物医药科技(上海)有限公司 2024-03-14 WO claimed
WO-2024032689-A1 COMPOUND BASED ON ISOINDOLINE-SUBSTITUTED GLUTARIMIDE BACKBONE AND USE THEREOF 标新生物医药科技(上海)有限公司 2024-02-15 WO claimed
WO-2023166485-A1 FUNGICIDAL COMBINATIONS, MIXTURES AND COMPOSITIONS AND USES THEREOF ADAMA MAKHTESHIM LTD. (IL) 2023-09-07 WO claimed
WO-2023151635-A1 COMPOUND BASED ON QUINAZOLINE-SUBSTITUTED GLUTARIMIDE SKELETON AND USE THEREOF 标新生物医药科技(上海)有限公司 2023-08-17 WO claimed
WO-2023066350-A1 CRBN E3 LIGASE LIGAND COMPOUND, PROTEIN DEGRADING AGENT DEVELOPED ON THE BASIS OF LIGAND COMPOUND, AND THEIR APPLICATIONS 标新生物医药科技(上海)有限公司 2023-04-27 WO claimed
WO-2023030170-A1 PROTEIN DEGRADATION COMPOUND BASED ON NAMPT TARGET PROTEIN AND APPLICATION THEREOF 标新生物医药科技(上海)有限公司 2023-03-09 WO claimed
US-20230051033-A1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CJB APPLIED TECHNOLOGIES, LLC 2023-02-16 US claimed
US-11083192-B2 Fertilizer and agrochemical formulation MITSUI CHEMICALS AGRO, INC. (JP) 2021-08-10 US claimed
WO-2006014135-A1 NOVEL PIPERIDINE DERIVATIVES AS HISTAMINE H3 RECEPTOR LIGANDS FOR TREATMENT OF DEPRESSION ASTRAZENECA AB (SE) 2006-02-09 WO claimed
WO-2006002022-A2 COMPOSITIONS AND METHODS USEFUL FOR THE TREATMENT OF HYPERGLYCEMIA IMMUSOL INCORPORATED (US) 2006-01-05 WO claimed
WO-2005082859-A1 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS ELI LILLY AND COMPANY (US) 2005-09-09 WO claimed
EP-1470131-A2 AMINOPIPERIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM GLAXO GROUP LIMITED (GB) 2004-10-27 EP claimed
US-20040102432-A1 Chemical compounds ASTRAZENECA AB (SE) 2004-05-27 US claimed
JP-2004508355-A 2004-03-18 JP claimed
WO-2003064431-A2 AMINOPIPERIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM GLAXO GROUP LIMITED (GB) 2003-08-07 WO claimed
EP-1322611-A1 CHEMICAL COMPOUNDS AstraZeneca AB (SE) 2003-07-02 EP claimed
US-6562844-B2 Attaching an olefin to a solid support; oxidizing the olefin to provide an epoxide functionality; opening the epoxide with an amine to form an amino alcohol; cyclizing the amino alcohol using a phosgene equivalent PHARMACIA & UPJOHN COMPANY 2003-05-13 US claimed
WO-2002020484-A1 CHEMICAL COMPOUNDS ASTRAZENECA AB (SE) 2002-03-14 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040102432-A1 Chemical compounds CCL11, HRH1, HRH4 ALDH1A1 429/4885CALM1 4408/4885RAB9A 1454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.