Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | CES2 | O00748 | 2/20 | 0.58 |
| ▸ | CES1 | P23141 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4849143 | 1.00 | LMNA (0.65) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL4850637 | 1.00 | LMNA (0.65) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL165161 | 0.79 | LMNA (1.00) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL21647917 | 0.79 | LMNA (1.00) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL5313046 | 0.79 | LMNA (1.00) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL8936450 | 0.79 | LMNA (0.71) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL29777368 | 0.79 | LMNA (1.00) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL255601 | 0.79 | LMNA (1.00) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL1050 | 0.79 | LMNA (1.00) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL3644 | 0.78 | LMNA (0.86) | LMNAMAPK1CES2CES1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4958018-A | REACTING A 3-HALOMETHYL-3-CEPHEM WITH A LEAD REDUCING AGENT | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1990-09-18 | — | — | US | claimed |
| US-4563450-A | CEPHALOSPORINS, MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-07 | — | — | US | claimed |
| EP-0033965-B1 | NEW CEPHEM COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-05-15 | — | — | EP | claimed |
| US-4407815-A | AMINO ACID DERIVATIVE ANTIBIOTICS | BEECHAM GROUP LIMITED (GB) | 1983-10-04 | — | — | US | claimed |
| EP-0033965-A2 | New cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-08-19 | — | — | EP | claimed |
| US-4072674-A | FOR CEPHALOSPORIN CONGENERS | SMITHKLINE CORPORATION (US) | 1978-02-07 | — | — | US | claimed |
| US-7825238-B2 | Antiviral methods employing double esters of 2′, 3′-dideoxy-3′-fluoroguanosine | MEDIVIR AB (SE) | 2010-11-02 | — | — | US | disclosed |
| EP-2079699-A1 | QUINOLINE DERIVATIVES | Envivo Pharmaceuticals, Inc. (US) | 2009-07-22 | — | — | EP | disclosed |
| EP-1319642-B1 | Method of Preparing a Halogenated Compound | OTSUKA KAGAKU KK (JP) | 2008-03-26 | — | — | EP | disclosed |
| WO-2008014602-A1 | QUINOLINE DERIVATIVES | ENVIVO PHARMACEUTICALS, INC. (US) | 2008-02-07 | — | — | WO | disclosed |
| EP-1132391-B1 | PROCESS FOR THE PREPARATION OF 3-SULFONYLOXY-3-CEPHEM COMPOUNDS | OTSUKA KAGAKU KK (JP) | 2006-11-15 | — | — | EP | disclosed |
| EP-1447406-B1 | 3-Cephem derivative crystal | OTSUKA KAGAKU KK (JP) | 2006-08-09 | — | — | EP | disclosed |
| US-7071173-B2 | Antiviral methods employing double esters of 2′, 3′-dideoxy-3′-fluoroguanosine | MEDIVIR AB (SE) | 2006-07-04 | — | — | US | disclosed |
| US-4041162-A | ANTIBIOTICS, BACTERICIDES | SMITHKLINE CORPORATION (US) | 1977-08-09 | — | — | US | disclosed |
| US-4034092-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |
| US-4025626-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |
| US-3994885-A | WITH ALKALI METAL ALKOXIDE, HALOGENATION | ELI LILLY AND COMPANY (US) | 1976-11-30 | — | — | US | disclosed |
| US-3985739-A | 3-Heterocyclic thiomethylcephalosporins | SMITHKLINE CORPORATION (US) | 1976-10-12 | — | — | US | disclosed |
| US-3976546-A | HYDROLYSIS, ESTERASE | GLAXO LABORATORIES LIMITED (EN) | 1976-08-24 | — | — | US | disclosed |
| US-3855213-A | 3-HETEROCYCLIC THIOMETHYL-CEPHALOSPORINS | SMITHKLINE BECKMAN CORPORATION | 1974-12-17 | — | — | US | disclosed |