Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.46 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.45 |
| ▸ | GLS | O94925 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | GCK | P35557 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3738472 | 0.93 | DGAT1 (0.49) | ESR2LMNARXFP1ALDH1A1GRAMD1A | |
| SCHEMBL3729696 | 0.93 | KMT2A (0.54) | SMN1; SMN2ESR2NPC1RAB9ALMNA | |
| SCHEMBL3726888 | 0.91 | ESR2 (0.47) | ESR2LMNARXFP1ALDH1A1GRAMD1A | |
| SCHEMBL3727461 | 0.90 | ESR2 (0.48) | SMN1; SMN2ESR2NPC1RAB9ALMNA | |
| SCHEMBL3725062 | 0.89 | ESR2 (0.47) | ESR2LMNARXFP1ALDH1A1GRAMD1A | |
| SCHEMBL3729675 | 0.88 | LMNA (0.48) | SMN1; SMN2ESR2NPC1RAB9ALMNA | |
| SCHEMBL3727174 | 0.88 | LMNA (0.48) | SMN1; SMN2ESR2NPC1RAB9ALMNA | |
| SCHEMBL3729473 | 0.87 | ESR2 (0.51) | SMN1; SMN2ESR2NPC1RAB9ALMNA | |
| SCHEMBL3728205 | 0.86 | ESR2 (0.47) | SMN1; SMN2ESR2NPC1RAB9ALMNA | |
| SCHEMBL3725240 | 0.86 | LMNA (0.47) | SMN1; SMN2ESR2NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | BOUILLOT ANNE MARIE JEANNE | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | SCD, SCD5, FADS2 | SMN1; SMN2 2732/4885ESR2 3678/4885NPC1 416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.