Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3729140 | 0.93 | SMN1; SMN2 (0.49) | KMT2ASMN1; SMN2NPC1RAB9AESR2 | |
| SCHEMBL3727461 | 0.92 | ESR2 (0.48) | KMT2ASMN1; SMN2NPC1RAB9AESR2 | |
| SCHEMBL3738472 | 0.92 | DGAT1 (0.49) | KMT2AESR2ALDH1A1MAPTLMNA | |
| SCHEMBL3727174 | 0.92 | LMNA (0.48) | KMT2ASMN1; SMN2NPC1RAB9AESR2 | |
| SCHEMBL3728205 | 0.90 | ESR2 (0.47) | KMT2ASMN1; SMN2NPC1RAB9AESR2 | |
| SCHEMBL3729653 | 0.90 | ESR2 (0.48) | KMT2ASMN1; SMN2NPC1RAB9AESR2 | |
| SCHEMBL3727225 | 0.90 | ESR2 (0.48) | KMT2ASMN1; SMN2NPC1RAB9AESR2 | |
| SCHEMBL3726888 | 0.90 | ESR2 (0.47) | KMT2AESR2ALDH1A1MAPTLMNA | |
| SCHEMBL3729473 | 0.90 | ESR2 (0.51) | KMT2ASMN1; SMN2NPC1RAB9AESR2 | |
| SCHEMBL3730968 | 0.89 | L3MBTL1 (0.51) | KMT2ASMN1; SMN2ESR2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | BOUILLOT ANNE MARIE JEANNE | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | SCD, SCD5, FADS2 | KMT2A 3443/4885SMN1; SMN2 2732/4885NPC1 416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.