Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | LMNA | P02545 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11771545 | 0.84 | RAB9A (0.68) | MAPTPOLBPKMALDH1A1LMNA | |
| SCHEMBL3275099 | 0.83 | ALDH1A1 (0.56) | MAPTPOLBPKMALDH1A1LMNA | |
| SCHEMBL30259514 | 0.81 | ELANE (0.70) | MAPTALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL9343618 | 0.80 | PKM (1.00) | MAPTPOLBPKMALDH1A1LMNA | |
| SCHEMBL14024262 | 0.80 | MAPT (0.77) | MAPTPOLBPKMALDH1A1LMNA | |
| SCHEMBL10628554 | 0.79 | ALDH1A1 (0.59) | MAPTPOLBPKMALDH1A1LMNA | |
| SCHEMBL1930857 | 0.79 | MAPT (0.74) | MAPTPOLBPKMALDH1A1LMNA | |
| SCHEMBL3161812 | 0.79 | MAPT (0.74) | MAPTPOLBPKMALDH1A1LMNA | |
| SCHEMBL3372297 | 0.77 | ALDH1A1 (0.58) | MAPTPOLBPKMALDH1A1LMNA | |
| SCHEMBL23651810 | 0.77 | MAPT (0.76) | MAPTALDH1A1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173715-A2 | USE OF PIPERIDINE DERIVATIVES AS AGONISTS OF CHEMOKINE RECEPTOR ACTIVITY | Euroscreen S.A. (BE) | 2010-04-14 | — | — | EP | disclosed |
| WO-2009010478-A2 | USE OF PIPERIDINE DERIVATIVES AS AGONISTS OF CHEMOKINE RECEPTOR ACTIVITY | EUROSCREEN S.A. (BE) | 2009-01-22 | — | — | WO | disclosed |