Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3729302 | 0.79 | MAPT (0.67) | ALDH1A1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL11771545 | 0.77 | RAB9A (0.68) | ALDH1A1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL9692767 | 0.76 | LMNA (0.69) | ALDH1A1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL30259514 | 0.75 | ELANE (0.70) | ALDH1A1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL691734 | 0.74 | ALDH1A1 (0.73) | ALDH1A1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL3275099 | 0.73 | ALDH1A1 (0.56) | ALDH1A1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL27996799 | 0.72 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL27877398 | 0.71 | ALDH1A1 (0.63) | ALDH1A1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL119176 | 0.71 | LMNA (1.00) | ALDH1A1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL23651810 | 0.71 | MAPT (0.76) | ALDH1A1LMNASMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4772692-A | AZETIDINONES | HOECHST UK LIMITED (GB) | 1988-09-20 | — | — | US | disclosed |
| EP-0069377-B1 | ANTIBACTERIAL PENEM DERIVATIVES | HOECHST UK LIMITED (GB) | 1988-06-22 | — | — | EP | disclosed |
| US-4585767-A | ANTIBIOTICS, BETA-LACTAMASE INHIBITORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-04-29 | — | — | US | disclosed |
| EP-0069377-A2 | Antibacterial penem derivatives | HOECHST UK LIMITED (GB) | 1983-01-12 | — | — | EP | disclosed |