Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL5076874 | 0.91 | ADORA1 (0.39) | ADORA1ADORA2ACA5APDE3BPDE3A | |
| SCHEMBL587003 | 0.78 | KMT2A (0.45) | ADORA1ADORA2ACA5APDE3BPDE3A | |
| SCHEMBL28647686 | 0.76 | PDE3B (0.45) | ADORA1ADORA2ACA5APDE3BPDE3A | |
| SCHEMBL4136622 | 0.74 | PDE3B (0.47) | ADORA1ADORA2ACA5APDE3BPDE3A | |
| SCHEMBL5076877 | 0.74 | CA12 (0.42) | ADORA1ADORA2ACA5APDE3BPDE3A | |
| SCHEMBL1983844 | 0.74 | ALDH1A1 (0.43) | CA5APDE3BPDE3ACA12CA9 | |
| SCHEMBL10327948 | 0.72 | ALDH1A1 (0.46) | ADORA1ADORA2ACA5ACYP3A4BLM | |
| SCHEMBL22719049 | 0.71 | ADORA1 (0.42) | ADORA1ADORA2ACA5ACYP3A4BLM | |
| SCHEMBL4136907 | 0.71 | CCR1 (0.48) | CA5APDE3BPDE3ACA12CA9 | |
| SCHEMBL11591796 | 0.70 | ADORA1 (0.53) | ADORA1ADORA2ACA5ACYP3A4BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025133660-A1 | NOVEL COMPOUNDS FOR HOST DIRECTED ANTIVIRAL STRATEGY | SORBONNE UNIVERSITE (FR) | 2025-06-26 | — | — | WO | disclosed |
| WO-2025132449-A1 | NOVEL COMPOUNDS FOR HOST DIRECTED ANTIVIRAL STRATEGY | SORBONNE UNIVERSITE (FR) | 2025-06-26 | — | — | WO | disclosed |
| US-20220112194-A1 | COMPOUNDS TARGETING PRMT5 | ALIGOS THERAPEUTICS, INC. | 2022-04-14 | — | — | US | disclosed |
| CN-114072407-A | Compounds targeting PRMT5 | 阿里戈斯治疗公司 | 2022-02-18 | — | — | CN | disclosed |
| US-20220048922-A1 | COMPOUNDS TARGETING PRMT5 | ALIGOS THERAPEUTICS, INC. | 2022-02-17 | — | — | US | disclosed |
| EP-3947388-A1 | COMPOUNDS TARGETING PRMT5 | Aligos Therapeutics, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |
| US-11198699-B2 | Compounds targeting PRMT5 | ALIGOS THERAPEUTICS, INC. (US) | 2021-12-14 | — | — | US | disclosed |
| US-11198699-B2 | Compounds targeting PRMT5 | ALIGOS THERAPEUTICS, INC. (US) | 2021-12-14 | — | — | US | disclosed |
| WO-2021202480-A1 | COMPOUNDS TARGETING PRMT5 | ALIGOS THERAPEUTICS, INC. (US) | 2021-10-07 | — | — | WO | disclosed |
| CN-113387962-A | Pyrazolo [3,4-d ] pyrimidine-3-one derivative, pharmaceutical composition and application thereof | 上海迪诺医药科技有限公司 | 2021-09-14 | — | — | CN | disclosed |
| WO-2008084324-A1 | NAPHTHYRIDINONE COMPOUND | PFIZER PRODUCTS INC. (US) | 2008-07-17 | — | — | WO | disclosed |
| US-20080167319-A1 | 7-(4-(4-[3-CHLORO-2-(TRIFLUOROMETHYL)PHENYL]PIPERAZIN-1-YL)BUTOXY)-[1,8]-NAPHTHYRIDIN-2(1H)-ONE | PFIZER INC. | 2008-07-10 | — | — | US | disclosed |
| US-20080167319-A1 | 7-(4-(4-[3-CHLORO-2-(TRIFLUOROMETHYL)PHENYL]PIPERAZIN-1-YL)BUTOXY)-[1,8]-NAPHTHYRIDIN-2(1H)-ONE | PFIZER INC. | 2008-07-10 | — | — | US | disclosed |
| US-20080167319-A1 | 7-(4-(4-[3-CHLORO-2-(TRIFLUOROMETHYL)PHENYL]PIPERAZIN-1-YL)BUTOXY)-[1,8]-NAPHTHYRIDIN-2(1H)-ONE | PFIZER INC. | 2008-07-10 | — | — | US | disclosed |
| EP-1609197-B1 | ORGANIC LIGHT EMITTING DEVICES UTILIZING BINUCLEAR METAL-COMPOUNDS AS EMISSIVE MATERIAL | UNIV SOUTHERN CALIFORNIA (US) | 2007-02-28 | — | — | EP | disclosed |
| US-20060269785-A1 | Binuclear compounds | THOMPSON MARK E | 2006-11-30 | — | — | US | disclosed |
| US-7090928-B2 | organic light emitting device wherein the emissive layer comprises a phosphorescent emitting material having a plurality of metal centers; flat panel displays, illumination, and backlighting | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2006-08-15 | — | — | US | disclosed |
| EP-1609197-A1 | ORGANIC LIGHT EMITTING DEVICES UTILIZING BINUCLEAR METAL-COMPOUNDS AS EMISSIVE MATERIAL | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004093210-A1 | ORGANIC LIGHT EMITTING DEVICES UTILIZING BINUCLEAR METAL-COMPOUNDS AS EMISSIVE MATERIAL | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2004-10-28 | — | — | WO | disclosed |
| US-20040197600-A1 | Binuclear compounds | THE UNIVERSITY OF SOUTHERN CALIFORNIA, (US) | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11198699-B2 | Compounds targeting PRMT5 | PRMT5, PRMT1, PRMT6 | ADORA1 3563/4885ADORA2A 4176/4885CA5A 1012/4885 |
| US-20220112194-A1 | COMPOUNDS TARGETING PRMT5 | PRMT5, PRMT1, PRMT6 | ADORA1 3563/4885ADORA2A 4176/4885CA5A 1012/4885 |
| US-20080167319-A1 | 7-(4-(4-[3-CHLORO-2-(TRIFLUOROMETHYL)PHENYL]PIPERAZIN-1-YL)BUTOXY)-[1,8]-NAPHTHYRIDIN-2(1H)-ONE | BDNF, SCN7A, GRIN2C | ADORA1 2423/4885ADORA2A 2887/4885CA5A 1891/4885 |
| US-20220048922-A1 | COMPOUNDS TARGETING PRMT5 | PRMT5, PRMT1, PRMT6 | ADORA1 3563/4885ADORA2A 4176/4885CA5A 1012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.