Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | ACR | P10323 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29584042 | 1.00 | ELANE (0.43) | ELANEATMCYP3A4LMNAPRSS1 | |
| SCHEMBL15836532 | 0.88 | ATM (0.48) | ELANEATMLMNAPRSS1ACR | |
| SCHEMBL15836493 | 0.87 | ELANE (0.42) | ELANEATMCYP3A4LMNAPRSS1 | |
| SCHEMBL10431306 | 0.86 | ELANE (0.41) | ELANEATMCYP3A4LMNAPRSS1 | |
| SCHEMBL28656823 | 0.83 | ELANE (0.40) | ELANEATMCYP3A4LMNAPRSS1 | |
| SCHEMBL28992157 | 0.83 | ELANE (0.46) | ELANEATMCYP3A4LMNAKMT2A | |
| SCHEMBL29584051 | 0.83 | ELANE (0.46) | ELANEATMCYP3A4LMNAPRSS1 | |
| SCHEMBL373997 | 0.83 | ELANE (0.46) | ELANEATMCYP3A4LMNAPRSS1 | |
| SCHEMBL373661 | 0.81 | ELANE (0.51) | ELANEATMLMNAPRSS1ACR | |
| SCHEMBL218655 | 0.81 | ELANE (0.56) | ELANEATMCYP3A4LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346594-B1 | SILICONE POLYMER FOR INTRAOCULAR LENSES WITH AMINE GROUPS | MENICON CO., LTD. (JP) | 2002-02-12 | — | — | US | claimed |
| EP-0600269-B1 | Soft ocular lens material | MENICON CO LTD (JP) | 1998-02-04 | — | — | EP | claimed |
| US-5416180-A | Fluorine containing (meth)acrylate polymers | MENICON CO., LTD. (JP) | 1995-05-16 | — | — | US | claimed |
| EP-0600269-A2 | Soft ocular lens material | Menicon Co., Ltd. (JP) | 1994-06-08 | — | — | EP | claimed |
| EP-3995493-B1 | CHROMENE COMPOUND AND PHOTOCHROMIC OPTICAL ARTICLE | TOKUYAMA CORP (JP) | 2024-07-03 | — | — | EP | disclosed |
| EP-2657304-B1 | AZO DYE, OCULAR LENS MATERIAL, METHOD FOR PRODUCING OCULAR LENS MATERIAL, AND OCULAR LENS | MENICON CO LTD (JP) | 2022-12-07 | — | — | EP | disclosed |
| US-20220213050-A1 | CHROMENE COMPOUND AND PHOTOCHROMIC OPTICAL ARTICLE | TOKUYAMA CORPORATION (JP) | 2022-07-07 | — | — | US | disclosed |
| EP-3995493-A1 | CHROMENE COMPOUND AND PHOTOCHROMIC OPTICAL ARTICLE | Tokuyama Corporation (JP) | 2022-05-11 | — | — | EP | disclosed |
| EP-3121643-B1 | OPHTHALMIC LENS | MENICON CO LTD (JP) | 2020-07-22 | — | — | EP | disclosed |
| US-20180356561-A1 | GEL, GEL MANUFACTURING METHOD, LENS, CONTACT LENS SURFACE MODIFIER, POLYMERIZABLE COMPOSITION, AND POLYMER | JSR CORPORATION (JP) | 2018-12-13 | — | — | US | disclosed |
| EP-2453292-B1 | SOFT HYBRID CONTACT LENS, METHOD FOR PRODUCING SAME, AND HYDRATION METHOD | MENICON CO LTD (JP) | 2016-09-07 | — | — | EP | disclosed |
| US-9034942-B2 | Polymer material, ophthalmic lens and contact lens | MENICON CO., LTD. (JP) | 2015-05-19 | — | — | US | disclosed |
| EP-0381005-B1 | Ocular lens material | MENICON CO LTD (JP) | 1995-01-11 | — | — | EP | disclosed |
| US-5346946-A | Polysiloxane macromonomer | MENICON CO., LTD (JP) | 1994-09-13 | — | — | US | disclosed |
| EP-0600269-A2 | Soft ocular lens material | Menicon Co., Ltd. (JP) | 1994-06-08 | — | — | EP | disclosed |
| EP-0584826-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1994-03-02 | — | — | EP | disclosed |
| EP-0584764-A1 | Ocular lens material | Menicon Co., Ltd. (JP) | 1994-03-02 | — | — | EP | disclosed |
| EP-0578087-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1994-01-12 | — | — | EP | disclosed |
| US-5041511-A | Vinyl benzene acrylate or methacrylate crosslinking agent | MENICON CO., LTD. (JP) | 1991-08-20 | — | — | US | disclosed |
| US-4954586-A | COPOLYMER OF A FLUORINE CONTAINING (METH)ACRYLATE, AN ALKYL (METH)ACRYLATE, A POLYSILOXANE AND A URETHANE CONTAINING POLYSILOXANE | MENICON CO., LTD (JP) | 1990-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213050-A1 | CHROMENE COMPOUND AND PHOTOCHROMIC OPTICAL ARTICLE | CRY1, CRY2, TRIP13 | ELANE 2505/4885ATM 929/4885CYP3A4 635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.