Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726789 | 0.76 | NPC1 (0.35) | MAPTLMNAPOLBCYP1A2CYP2C19 | |
| SCHEMBL3725190 | 0.73 | HTR2A (0.36) | CYP1A2CYP2C19HTR2AHTR2CGAA | |
| SCHEMBL3155407 | 0.73 | GAA (0.37) | LMNAPOLBCYP1A2HTR2AHTR2C | |
| SCHEMBL4226263 | 0.70 | KCNH2 (0.34) | LMNAPOLBCYP1A2HTR2AHTR2C | |
| SCHEMBL3165337 | 0.70 | HTR2A (0.44) | LMNAPOLBCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL18151130 | 0.70 | GAA (0.34) | LMNAPOLBCYP1A2HTR2AHTR2C | |
| SCHEMBL3736131 | 0.70 | LRRK2 (0.35) | LMNAPOLBCYP1A2HTR2AHTR2C | |
| SCHEMBL3735745 | 0.66 | KDM4E (0.34) | MAPTCYP1A2ALDH1A1HTR2AHTR2C | |
| SCHEMBL3159391 | 0.66 | ADORA2A (0.50) | MAPTLMNACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL27672808 | 0.65 | RAB9A (0.46) | MAPTLMNAPOLBHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879878-B1 | HETEROCYCLYLETHYLHETEROCYCLYLCARBOXAMIDE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2014-06-25 | — | — | EP | disclosed |
| EP-2518065-A1 | N-(furanylethyl)-heterocyclylcarboxamide derivatives as fungicides | Bayer CropScience AG (DE) | 2012-10-31 | — | — | EP | disclosed |
| US-7825068-B2 | Heterocyclylethylcarboxamide derivatives | BAYER CROPSCIENCE AG (DE) | 2010-11-02 | — | — | US | disclosed |
| US-20090054492-A1 | Heterocyclyethylcarboxamide Derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2009-02-26 | — | — | US | disclosed |
| EP-1879878-A2 | NEW HETEROCYCLYLETHYLCARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108791-A2 | HETEROCYCLYLETHYLHETEROCYCLYLCARBOXAMIDE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2006-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054492-A1 | Heterocyclyethylcarboxamide Derivatives | CYP51A1, CYP1A2, CYP3A7 | MAPT 2141/4885LMNA 2731/4885POLB 4159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.