Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722109 | 0.84 | IKBKE (0.41) | SLC6A4 | |
| SCHEMBL24252451 | 0.79 | ALDH1A1 (0.56) | HPGDKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL30451941 | 0.79 | ALDH1A1 (0.56) | HPGDKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL30712291 | 0.77 | C5AR1 (0.53) | HPGDPPARGALDH1A1 | |
| SCHEMBL28410322 | 0.77 | C5AR1 (0.53) | HPGDPPARGALDH1A1 | |
| SCHEMBL3718915 | 0.77 | HPGD (0.49) | HPGDF2PLAUST14KDM4E | |
| SCHEMBL12603170 | 0.76 | S1PR2 (0.51) | HPGDF2PLAUST14KDM4E | |
| SCHEMBL1390849 | 0.75 | NFE2L2 (0.53) | HPGD | |
| SCHEMBL4682048 | 0.73 | ACACB (0.48) | PPARGKDM4EALDH1A1 | |
| SCHEMBL1390954 | 0.73 | MAPT (0.49) | HPGDKDM4EMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280067-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | SARMA PAKALA KUMARA SAVITHRU | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280067-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | ACACA, ACACB, PC | HPGD 672/4885SLC6A4 4358/4885PIM1 2794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.