Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | BTK | Q06187 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3734379 | 0.91 | DHODH (0.45) | L3MBTL1GAAAURKBPKN1PKN2 | |
| SCHEMBL39083 | 0.84 | DHODH (0.61) | RAB9ANPC1GAAHDAC6DHODH | |
| SCHEMBL6574358 | 0.76 | L3MBTL1 (0.57) | KDM4EHSD17B10L3MBTL1GAAHPGD | |
| SCHEMBL989259 | 0.75 | L3MBTL1 (0.40) | KDM4EL3MBTL1HPGDCDK2DHODH | |
| SCHEMBL172216 | 0.75 | NPC1 (1.00) | RAB9AKDM4ENPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30634854 | 0.75 | NPC1 (1.00) | RAB9AKDM4ENPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30561047 | 0.75 | NPC1 (1.00) | RAB9AKDM4ENPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6519737 | 0.75 | ALDH1A1 (0.42) | KDM4EALDH1A1SMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL3738884 | 0.75 | HDAC6 (0.63) | RAB9AKDM4ENPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4360279 | 0.75 | HDAC6 (0.76) | RAB9AKDM4ENPC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100279122-A1 | Benzimidazole, Benzoxazole and Benzothiazole Derivatives, Optical Film Comprising them and Method of Producing thereof | CRYSOPTIX KK (JP) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279122-A1 | Benzimidazole, Benzoxazole and Benzothiazole Derivatives, Optical Film Comprising them and Method of Producing thereof | BMX, ABCG2, BRI3BP | RAB9A 2720/4885KDM4E 1712/4885NPC1 3022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.