SCHEMBL989259

SCHEMBL989259

O=S(=O)(O)c1cccc2[nH]c(S)nc12

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.40
TTR P02766 2/20 0.35
KDM4E B2RXH2 1/20 0.35
HPGD P15428 1/20 0.35
DHODH Q02127 4/20 0.34
PARP1 P09874 7/20 0.33
FABP4 P15090 1/20 0.33
CCNA2 P20248 1/20 0.33
CDK2 P24941 1/20 0.33
MAPK14 Q16539 1/20 0.33
NR4A1 P22736 1/20 0.32
ALOX12 P18054 1/20 0.31
COMT P21964 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8034262 0.83 PTGS1 (0.37) KDM4EHPGDDHODHPARP1ALOX12
SCHEMBL3734379 0.83 DHODH (0.45) L3MBTL1DHODHPARP1
SCHEMBL11327139 0.82 DUSP5 (0.35) KDM4EHPGDDHODHPARP1
Silver SCHEMBL9320049 0.82 PARP1 (0.33) KDM4EHPGDDHODHPARP1
SCHEMBL6574358 0.81 L3MBTL1 (0.57) L3MBTL1TTRKDM4EHPGDDHODH
SCHEMBL11234305 0.79 PARP1 (0.53) L3MBTL1KDM4EDHODHPARP1
SCHEMBL39083 0.76 DHODH (0.61) DHODHPARP1
SCHEMBL9394277 0.76 PSMB8 (0.56) L3MBTL1TTRKDM4EHPGDDHODH
SCHEMBL6519737 0.76 ALDH1A1 (0.42) L3MBTL1TTRKDM4EHPGDDHODH
SCHEMBL8712895 0.76 FEN1 (0.41) KDM4ECOMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9428545-B2 Process for isolation of plasma or serum proteins THERAPURE BIOPHARMA INC. (CA) 2016-08-30 US claimed
US-20160128944-A1 COATED PARTICLES AND COMPOSITIONS COMPRISING SAME VYOME THERAPEUTICS LIMITED (IN) 2016-05-12 US claimed
EP-3003031-A1 COATED PARTICLES AND COMPOSITIONS COMPRISING SAME Vyome Biosciences Pvt Ltd (IN) 2016-04-13 EP claimed
CN-105407718-A Coated particles and compositions comprising the same VYOME BIOSCIENCES 2016-03-16 CN claimed
US-20160009757-A1 PROCESS FOR ISOLATION OF PLASMA OR SERUM PROTEINS THERAPURE BIOPHARMA INC. (CA) 2016-01-14 US claimed
WO-2014195872-A1 COATED PARTICLES AND COMPOSITIONS COMPRISING SAME VYOME BIOSCIENCES PVT. LTD. (IN) 2014-12-11 WO claimed
EP-1765866-B1 ISOLATION OF PLASMA OR SERUM PROTEINS THERAPURE BIOPHARMA INC (CA) 2014-01-08 EP claimed
EP-2788006-B1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS INC (US) 2026-01-07 EP disclosed
EP-4674856-A2 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS Alnylam Pharmaceuticals, Inc. (US) 2026-01-07 EP disclosed
EP-4635481-A2 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS Alnylam Pharmaceuticals, Inc. (US) 2025-10-22 EP disclosed
EP-4218722-B1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS INC (US) 2025-08-20 EP disclosed
US-12364762-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2025-07-22 US disclosed
US-12350338-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2025-07-08 US disclosed
US-4699873-A HYDRAZINE DERIVATIVE COMPOUND AND DISULFIDE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1987-10-13 US disclosed
US-4681836-A RHODIUM SALT, HYDRAZINE DERIVATIVE FUJI PHOTO FILM CO., LTD. (JP) 1987-07-21 US disclosed
EP-0196626-A2 Silver halide photographic material and method for forming an ultrahigh contrast negative image therewith FUJI PHOTO FILM CO., LTD. (JP) 1986-10-08 EP disclosed
EP-0154293-A2 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1985-09-11 EP disclosed
EP-0138200-A2 Silver halide photographic material and method for forming high contrast negative image using the same FUJI PHOTO FILM CO., LTD. (JP) 1985-04-24 EP disclosed
US-4332878-A USING A HYDROQUINONE DERIVATIVE IN THE SILVER HALIDE EMULSION LAYER AND DEVELOPING IN THE PRESENCE OF A HYDRAZINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1982-06-01 US disclosed
US-4323643-A HIGH CONTRAST USING UREIDO ARYLHYDRAZIDE COMPOUNDS FUJI PHOTO FILM CO., LTD. (JP) 1982-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12350338-B2 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP L3MBTL1 1228/4885TTR 1516/4885KDM4E 4402/4885
US-12364762-B2 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP L3MBTL1 1228/4885TTR 1516/4885KDM4E 4402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.