Sugi Predict

Sugi Predict / Compounds / SCHEMBL39083

SCHEMBL39083

SCHEMBL39083

O=S(=O)(O)c1cccc2[nH]c(-c3ccccc3)nc12

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ DHODH Q02127 11/20 0.61
▸ PARP1 P09874 5/20 0.57
▸ HDAC6 Q9UBN7 1/20 0.52
▸ GAA P10253 2/20 0.47
▸ NPC1 O15118 1/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ CHEK2 O96017 1/20 0.46
▸ MGAM O43451 1/20 0.46
▸ SI P14410 1/20 0.46
▸ MGAM2 Q2M2H8 1/20 0.46
▸ CYP1A2 P05177 1/20 0.45
▸ CYP2D6 P10635 1/20 0.45
▸ GRIN2B Q13224 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3734379 0.89 DHODH (0.45) DHODHPARP1GAACHEK2MGAM
SCHEMBL275643 0.84 HDAC6 (0.49) DHODHPARP1HDAC6GAAMGAM
SCHEMBL9289139 0.84 DHODH (0.52) DHODHPARP1HDAC6GAANPC1
SCHEMBL3734375 0.84 RAB9A (0.56) DHODHHDAC6GAANPC1RAB9A
SCHEMBL6363407 0.84 DHODH (0.56) DHODHPARP1HDAC6GAANPC1
SCHEMBL6575742 0.81 HDAC6 (0.63) DHODHPARP1HDAC6GAANPC1
SCHEMBL1298432 0.78 DHODH (0.94) DHODHPARP1
SCHEMBL6574358 0.78 L3MBTL1 (0.57) DHODHPARP1GAA
SCHEMBL989259 0.76 L3MBTL1 (0.40) DHODHPARP1
SCHEMBL39084 0.76 HDAC6 (0.52) DHODHPARP1HDAC6GAANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 959 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676428-A1 LIQUID UV FILTER COMPOSITION CONTAINING DIOLS Symrise AG (DE) 2026-01-14 — — EP claimed
EP-4676433-A1 LIQUID UV FILTER CONCENTRATE Symrise AG (DE) 2026-01-14 — — EP claimed
US-11723850-B2 Liquid and transparent blend of UV filters Symrise, AG (DE) 2023-08-15 — — US claimed
US-11559557-B2 Medicament comprising ginger root CO2 extract SYMRISE AG (DE) 2023-01-24 — — US claimed
US-20220354772-A1 BLEND OF BEESWAX AND A LACTYLATE ESTER SYMRISE AG (DE) 2022-11-10 — — US claimed
EP-3993767-A1 BLEND OF BEESWAX AND A LACTYLATE ESTER Symrise AG (DE) 2022-05-11 — — EP claimed
US-20220071872-A1 A LIQUID AND TRANSPARENT BLEND OF UV FILTERS SYMRISE AG (DE) 2022-03-10 — — US claimed
EP-3873622-A1 A LIQUID AND TRANSPARENT BLEND OF UV FILTERS Symrise AG (DE) 2021-09-08 — — EP claimed
CN-113164792-A Liquid transparent mixtures of UV filters 西姆莱斯股份公司 2021-07-23 — — CN claimed
WO-2021001029-A1 BLEND OF BEESWAX AND A LACTYLATE ESTER SYMRISE AG (DE) 2021-01-07 — — WO claimed
US-6440401-B1 2-PHENYLBENZIMIDAZOLEDI- AND TRISULFONIC ACIDS; COSMETIC FORMULATIONS MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 2002-08-27 — — US claimed
WO-2002038537-A1 NOVEL INDANYLIDENE COMPOUNDS HAARMANN & REIMER GMBH (DE) 2002-05-16 — — WO claimed
US-20020055532-A1 UV-B filter MERCK PATENT GESELLSCHAFT (DE) 2002-05-09 — — US claimed
US-20020016349-A1 UV-B filters MERCK PATENT GESELLSCHAFT (DE) 2002-02-07 — — US claimed
EP-1167358-A1 2-Phenylbenzimidazole sulphonic acids as UV-B filters MERCK PATENT GmbH (DE) 2002-01-02 — — EP claimed
WO-2001093822-A2 AQUEOUS DISPERSIONS OF NANO-PARTICULATE UV-FILTERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-13 — — WO claimed
US-6153174-A Cosmetic compositions comprising a combination of UV absorbers BASF AKTIENGESELLSCHAFT (DE) 2000-11-28 — — US claimed
US-6123929-A A COSMETIC SUNSCREEN COMPRISES IN AN AQUEOUS PHASE A 2-PHENYLBENZIMIDAZOLE SULFONIC ACID OR SALT AND A FATTY PHASE CONTAINING A LINEAR OR CYCLIC MODIFIED POLYSILOXANE ROCHE VITAMINS INC. (US) 2000-09-26 — — US claimed
EP-0979645-A1 Light screening composition containing a polysiloxane type UV-B screening agent and a benzimidazol type UV-B screening agent F. HOFFMANN-LA ROCHE AG (CH) 2000-02-16 — — EP claimed
EP-0838214-A2 Cosmetic compositions containing a combination of UV-absorbers including a triazine derivative BASF AKTIENGESELLSCHAFT (DE) 1998-04-29 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11559557-B2 Medicament comprising ginger root CO2 extract CRY1, GRK1, GPER1 DHODH 3047/4885PARP1 2136/4885HDAC6 2552/4885
US-20020055532-A1 UV-B filter CBR1, UQCRB, H1-0 DHODH 1470/4885PARP1 1843/4885HDAC6 2469/4885
US-20220354772-A1 BLEND OF BEESWAX AND A LACTYLATE ESTER LAGE3, CRY1, BROX DHODH 1354/4885PARP1 2451/4885HDAC6 3827/4885
US-20020016349-A1 UV-B filters CBR1, H1-0, CYP1B1 DHODH 1438/4885PARP1 1798/4885HDAC6 2506/4885
US-11723850-B2 Liquid and transparent blend of UV filters F2, F12, F10 DHODH 1774/4885PARP1 2961/4885HDAC6 2926/4885
US-20220071872-A1 A LIQUID AND TRANSPARENT BLEND OF UV FILTERS F2, F12, TYR DHODH 1710/4885PARP1 3064/4885HDAC6 3012/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.