Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 5/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PTDSS1 | P48651 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3750862 | 0.82 | KDR (0.40) | CYP2D6KDRCHEK1MGAT2CYP3A4 | |
| SCHEMBL2966206 | 0.78 | KDM4E (0.45) | KDRCHEK1KDM4EPDGFRBPDGFRA | |
| SCHEMBL3742853 | 0.77 | KDR (0.43) | CYP2D6KDRCHEK1CYP3A4MOGAT2 | |
| SCHEMBL3739265 | 0.76 | KDR (0.44) | CYP2D6KDRCHEK1CYP3A4MOGAT2 | |
| SCHEMBL6782454 | 0.73 | RAB9A (0.51) | KDRCHEK1KDM4EPDGFRBPDGFRA | |
| SCHEMBL3741501 | 0.68 | SCN8A (0.37) | CYP2D6CYP3A4MOGAT2MAOB | |
| SCHEMBL10916948 | 0.66 | KDR (0.47) | KDRCHEK1KDM4EPDGFRBALDH1A1 | |
| SCHEMBL11057025 | 0.66 | DAO (0.54) | KDRCHEK1KDM4EPDGFRBPDGFRA | |
| SCHEMBL3748480 | 0.66 | CTSV (0.58) | CYP2D6KDM4EALDH1A1HPGDMAOB | |
| SCHEMBL3745791 | 0.64 | MOGAT2 (0.35) | CYP2D6CYP3A4MOGAT2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829578-B1 | Aromatic ketones and uses thereof | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2010-11-09 | — | — | US | disclosed |