Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 5/20 | 0.58 |
| ▸ | CTSL | P07711 | 5/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | KIF11 | P52732 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3735320 | 0.88 | MAOB (0.53) | CTSVCTSLCYP2D6MAOBMAOA | |
| SCHEMBL13438381 | 0.85 | MAOB (0.53) | CTSVCTSLCYP2D6MAOBMAOA | |
| SCHEMBL3738315 | 0.82 | MAOB (0.47) | CTSVCTSLCYP2D6MAOBMAOA | |
| SCHEMBL9625788 | 0.81 | KIF11 (0.57) | CTSVCTSLCYP2D6KIF11MAOA | |
| SCHEMBL13438382 | 0.76 | MAOB (0.42) | CTSVCTSLCYP2D6MAOBMAOA | |
| SCHEMBL4486207 | 0.76 | CTSV (0.70) | CTSVCTSLCYP2D6KIF11MAOA | |
| SCHEMBL3615103 | 0.76 | XDH (0.64) | CTSVCTSLCYP2D6MAOBMAOA | |
| SCHEMBL3735330 | 0.76 | MAOB (0.59) | MAOB | |
| SCHEMBL13656510 | 0.75 | GABRP (0.57) | CTSVCTSLCYP2D6KIF11KDM4E | |
| SCHEMBL3745105 | 0.74 | MDH2 (0.60) | ALDH1A1HTTHPGDSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829578-B1 | Aromatic ketones and uses thereof | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2010-11-09 | — | — | US | disclosed |