Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3732169 | 0.82 | RXFP1 (0.36) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL3738062 | 0.78 | NPC1 (0.45) | BTKNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL3739269 | 0.76 | MAOB (0.36) | NPC1RAB9AKDM4ETLR8MEN1 | |
| SCHEMBL11053518 | 0.76 | CA12 (0.39) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL3742855 | 0.76 | MAOB (0.36) | NPC1RAB9AKDM4ETLR8MEN1 | |
| SCHEMBL3366108 | 0.74 | NPC1 (0.42) | BTKNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL6245655 | 0.73 | RAB9A (0.41) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL11061072 | 0.73 | TLR8 (0.38) | NPC1RAB9AKDM4ETLR8HPGD | |
| SCHEMBL28054211 | 0.71 | NPC1 (0.39) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL6238756 | 0.70 | BTK (0.41) | BTKNPC1RAB9AKDM4ETLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829578-B1 | Aromatic ketones and uses thereof | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2010-11-09 | — | — | US | disclosed |
| EP-1353908-B1 | PROCESSES AND SYNTHETIC INTERMEDIATES FOR PREPARING N-ARYLACRIDANCARBOXYLIC ACID DERIVATIVES | LUMIGEN INC (US) | 2006-03-08 | — | — | EP | disclosed |
| EP-1353908-A4 | PROCESSES AND SYNTHETIC INTERMEDIATES FOR PREPARING N-ARYLACRIDANCARBOXYLIC ACID DERIVATIVES | LUMIGEN INC (US) | 2004-01-28 | — | — | EP | disclosed |
| EP-1353908-A1 | PROCESSES AND SYNTHETIC INTERMEDIATES FOR PREPARING N-ARYLACRIDANCARBOXYLIC ACID DERIVATIVES | LUMIGEN, INC. (US) | 2003-10-22 | — | — | EP | disclosed |
| WO-2002059096-A1 | PROCESSES AND SYNTHETIC INTERMEDIATES FOR PREPARING N-ARYLACRIDANCARBOXYLIC ACID DERIVATIVES | LUMIGEN, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
| US-6410732-B2 | FORMATION OF BOND BETWEEN NITROGEN ATOM OF ACRIDAN RING AND CARBON ATOM OF ANOTHER AROMATIC OR HETEROAROMATIC RING COMPOUND; ASSAYS FOR PEROXIDASE ENZYMES AND ENZYME INHIBITORS AND IN ASSAYS EMPLOYING ENZYME-LABELED SPECIFIC BINDING PAIRS | LUMIGEN, INC. | 2002-06-25 | — | — | US | disclosed |
| US-20010031869-A1 | Processes and synthetic intermediates for preparing N-arylacridancarboxylic acid derivatives | LUMIGEN, INC. | 2001-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031869-A1 | Processes and synthetic intermediates for preparing N-arylacridancarboxylic acid derivatives | ALDH3A1, AADAC, SPR | BTK 3198/4885NPC1 4631/4885RAB9A 4128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.