Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.52 |
| ▸ | GRM5 | P41594 | 2/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4508979 | 0.85 | GRM5 (0.58) | ITGB3ITGA2BGRM5AOC3 | |
| SCHEMBL3725254 | 0.85 | ITGB3 (0.54) | ITGB3ITGA2BGRM5GRM2 | |
| SCHEMBL3723214 | 0.83 | ITGB3 (0.54) | ITGB3ITGA2BGRM5GRM2AOC3 | |
| SCHEMBL3722125 | 0.81 | ITGB3 (0.50) | ITGB3ITGA2BGRM5GRM2AOC3 | |
| SCHEMBL3725624 | 0.79 | ITGB3 (0.53) | ITGB3ITGA2BGRM5GRM2 | |
| SCHEMBL3722121 | 0.78 | ITGB3 (0.48) | ITGB3ITGA2BGRM5GRM2 | |
| SCHEMBL4490327 | 0.78 | HRH3 (0.46) | ITGB3ITGA2BGRM5AOC3 | |
| SCHEMBL7799399 | 0.76 | ITGB3 (0.64) | ITGB3ITGA2B | |
| SCHEMBL5284246 | 0.74 | GRIN2B (0.46) | ITGB3ITGA2BGRM5ADAM17 | |
| SCHEMBL3729890 | 0.74 | ACACB (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127212-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |
| US-20100280067-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | SARMA PAKALA KUMARA SAVITHRU | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280067-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | ACACA, ACACB, PC | ITGB3 4238/4885ITGA2B 4459/4885GRM5 2856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.